Hamilton Robotics in Partnership with GE Healthcare Revolutionizes Automated Biological Sample Card Punching with the easyPunch STARlet System

15 Nov 2012

Product news

Hamilton Robotics in collaboration with GE Healthcare Life Sciences introduces the easyPunch STARlet™ workstation, the first fully automated system integrating sample card punching and liquid handling into one easy workflow.

The easyPunch STARlet system, manufactured in Hamilton’s Bonaduz, Switzerland facility, seamlessly integrates punching of GE Healthcare Whatman FTATM and DMPK sample collection cards with automated sample extraction, eliminating common bottlenecks in laboratory processes. The system minimizes human error and enables high-throughput sample preparation for a variety of applications, such as forensic reference databasing as well as pre-clinical and clinical drug metabolism and pharmacokinetics (DMPK) and toxicology studies.

“Because many labs lack a fully automated workflow, thousands of samples such as blood and saliva placed on punch cards are waiting long periods to be processed for critical studies and forensic analysis,” says Stefan Mauch, Product Manager of the easyPunch STARlet system. "Until now, sample card punching for analysis preparation required tedious manual work or separate semi-automated instruments and an operator. Researchers or technicians had to be consistently precise and experienced when handling and tracking samples, or the results could be compromised.”

The easyPunch workstation is based on the Hamilton Robotics Microlab® STARlet platform and features two special modules and robotic arms for transporting and punching paper cards. The samples are monitored by powerful tracking software to eliminate any chance of sample identification errors. The entire process is tracked using imaging recognition. Hamilton’s proprietary software, based on industrial machine vision technology, provides complete control and monitoring of the punching process. The software recognizes the position and size of the card, identifies the sample by reading the barcode, and determines the punch area. The workstation also takes a picture of the target well to ensure the punch has arrived in the designated well.

Compatibility with library information management systems (LIMS) and full traceability ensure that data can be linked confidently to each sample. The modular nature of the system enables integration of other devices, such as a centrifuge and a plate sealer, thus potentially integrating the entire workflow.

“Ease of use makes this workstation an attractive solution for repetitive tasks in forensic and biopharma sample handling,” says Navjot Kaur, Product Manager at Hamilton Robotics in Reno, Nevada. “Currently technicians manually clean between samples, but the easyPunch STARlet system performs this step automatically, reducing cross-contamination. Barcode reading and imaging support full traceability and reporting of samples, both during punching and downstream processing.”

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Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Evidence Collection and AnalysisEvidence Collection and Analysis is the retrieval and subsequent investigation into criminal evidence obtained from a crime scene. Forensic genetic instruments, kits and reagents enable the analysis of evidence collected  at the crime scene. Reagents and kits for presumptive analysis for body fluids such as blood, saliva and semen in addition to drugs and narcotics test kits are used for CSI. Fingerprinting equipment, forensic light sources, casting kits and equipment for collecting recoverable materials can be found in the directory.Toxicology / Drugs of Abuse TestingToxicology and Drugs of Abuse Testing is the investigation into toxic and illegal substances found at the scene of a crime or from a suspect and / or victim associated with a scene of a crime. Analyzers, immunoassays and drugs of abuse test kits and presumptive test kits are an essential aspect of toxicology investigation.PharmacokineticsDrug MetabolismDrug metabolism is the enzymatic conversion within the body of pharmaceutical substances into other chemical compounds. The primary site for drug metabolism is the liver.Forensic InvestigationForensic investigation is a diverse collection of scientific techniques and methods for the identification and characterization of chemicals relating to crime scene investigations.Blood AnalysisThe analysis of blood is vital for many areas of life sciences and forensic investigations. Blood samples can be tested for a number of different reasons such as diagnosis, glucose levels, cholesterol and drug testing.LIMsBarcoded Samples
Hamilton Robotics in Partnership with GE Healthcare Revolutionizes Automated Biological Sample Card Punching with the easyPunch STARlet System