Gyros Protein Technologies introduces Gyrolab Bioaffy 4000 CD to extend sensitivity of immunoassay CD range

Enables researchers to generate more data in less time to support both preclinical and clinical studies

28 Jan 2021
Tom Casburn
Associate Editor

Product news

Gyros Protein Technologies AB, a pioneer in automated nanoliter-scale immunoassays and a leading provider of peptide synthesizers and reagents, has announced the introduction of Gyrolab® Bioaffy™ 4000 CD for immunoassay applications in biotherapeutic workflows. The new Gyrolab Bioaffy 4000, with a 4000 nL sample volume, is based on the proven design of Gyrolab Bioaffy 1000 CD, allowing seamless assay transfer between CD types and enabling researchers to improve productivity.

The new CD adds to the Company’s existing immunoassay technology, including Gyrolab Bioaffy CDs, which together cover broad analytical ranges of more than 6 logs. Gyrolab Bioaffy 4000 CD is designed to meet customer requests for extended sensitivity for more demanding analytical needs, such as PK (pharmacokinetics) assays requiring higher sensitivity and biomarker quantification. This new CD offers assay sensitivity down to at least the low pg/mL range and can be used as part of a Gyroplex™ panel where up to five singleplex biomarker assays (or any combination of assays) can be separately developed and validated for sample analysis in the same run under the conditions that are optimal for that particular assay. Researchers can now generate more data in less time for a broader range of analytical applications, helping to speed the development of novel biotherapeutics, including cell and gene therapies.

Mark Vossenaar, Vice President, General Manager, Gyros Protein Technologies, commented: “The addition of Gyrolab Bioaffy 4000 CD to our Bioaffy CD family represents our commitment to developing new high value products, which enable customers to improve productivity in their development of safer and more efficacious biotherapies and vaccines. We believe this new CD will address the demand, especially in phases 1 – 3 clinical trials, for increased flexibility, compatibility with various matrices, and the possibility of running individual optimized assays with no cross-talk between assays or samples - enabling the confident analysis of different analytes with widely varied concentrations in the same run.”

Gyrolab Bioaffy CDs form the core of Gyrolab immunoassay technology, which is used by a majority of the world’s leading biopharmaceutical companies, CROs and CMOs. Gyrolab CD-based immunoassay technology accelerates biopharmaceutical development and production, and delivers the performance needed for time critical workflows, including rapid assay development, handling small sample and reagent volumes, and the ability to measure over a broad dynamic range with minimal matrix interference.

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.BiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.