Gyros Protein Technologies adds Gyrolab Biomarker Kits to expand range of ready-to-use kits and reagents

Single analyte biomarker kit reagents introduced for the quantification of five human inflammatory cytokines

1 Dec 2022
Dora Wells
Clinical Content Editor

Product news

Gyros Protein Technologies, a leading provider of peptide synthesizers and reagents and a pioneer in automated nanoliter-scale immunoassays, introduces Gyrolab® Human Cytokine Kit Reagents, the first in a range of new biomarker kits. These include five single analyte biomarker kit reagents for the quantification of human inflammatory cytokines: human TNF-alpha, IFN-gamma, IL-6, IL-10 and IL-4. The new Gyrolab Human Cytokine Kit Reagents are optimized for use on all Gyrolab systems, offer improved assay performance, and meet key customer needs to face the biomarker assay development challenges encountered during drug development programs and regulatory studies.

Adding to the Company’s existing range of high-quality ready-to-use kits and solutions, the new kits enable high quality data to be generated through well characterized kit reagents and standards, whilst providing a high sensitivity and wide dynamic range to cover the full spectrum of cytokine levels seen in disease states or pharmacodynamic studies. The Gyrolab Biomarker Kits offer convenience and an expedited analytical solution for biomarker quantification by removing the need for assay development. High throughput and automated analyses reduce manual intervention, enable short turnaround times and accelerate data-driven decisions.

As the use of biomarkers in biotherapeutic development continues to increase, single analyte assays with high reproducibility are in high demand. To date, customers have been using the open Gyrolab platform for development of biomarker assays. The introduction of new plug and play kits increase the utility of the platform by removing the timelines needed for assay development and offer a combination of advantages to meet the customer needs in the area.

Mark Vossenaar, General Manager Biopharmaceutical Development Division, Gyros Protein Technologies, commented: “Biomarker assay development is time and resource intensive, requires a high level of expertise, and often comes at a high cost. This is why commercial immunoassay kits are growing in popularity. The introduction of the five new Gyrolab Human Cytokine Kit Reagents as first in a growing range of biomarker kits represents our commitment to building on the Company’s proven expertise to implement innovative technologies that enable scientists to quickly generate high quality biomarker data utilized for critical decision making for drug safety and efficacy."

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BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Protein QuantificationThe detection and quantification of proteins in a sample is vital across life sciences, pharmaceutical research and clinical diagnostics, and a variety of equipment is available to scientists to simplify the workflow. Proteins of interest can be easily labeled and detected on light-based detection instruments. Immunoassay kits allow you to identify a specific protein of interest and protein detection beads or antibody microarrays allow you to identify multiple specific proteins at once. Protein interactions and enzyme activity can also be monitored with protein-protein interaction assays. Additionally, the biophysical characterization of proteins is made easy with biokinetic analyzers. Find the best protein detection and quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.CytokinesCytokines are signaling proteins critical for cell communication in the immune system. They regulate inflammation, immune responses, and cell growth. Cytokine research is vital for understanding disease mechanisms and developing therapies. Explore tools for cytokine detection and analysis in our directory.InflammationBiomarker Discovery
Gyros Protein Technologies adds Gyrolab Biomarker Kits to expand range of ready-to-use kits and reagents