Guy’s and St Thomas’ NHS Foundation Trust Update Their Biological Sample Storage Systems

8 Feb 2017
Mia Harley
Biochemist

Industry news

The Biorepository at the Guy’s and St Thomas’ Bioresource stores a variety of samples, including whole blood, plasma and sera. With some 30,000 samples from 5,200 volunteers and patients now collected, a Matrix Gemini Laboratory Information Management System (LIMS) from Autoscribe Informatics has been implemented to manage all aspects of sample handling and allow the most efficient use of freezer storage space. System actions include sample tracking, location recording and chain of custody reporting with full audit trails of all activities.

Autoscribe Informatics has published a new case study highlighting the use of Matrix Gemini for this application. The Guy’s and St Thomas’ BioResource facility provides expertise on all aspects of the collection of human samples. It is part of the National Institute for Health Research (NIHR) BioResource which operates across eight centres in the UK and aims to establish cohorts of healthy volunteers and patients who have provided clinical information and biological samples and who can be invited to participate in experimental medicine studies.

“We have extensive experience of implementing biobanking solutions,” commented John Boother, President of Autoscribe Informatics. “This means that we were able to demonstrate real-world biobank workflows to Guy’s and St Thomas’ staff and were able to work closely with them to use the Matrix configuration tools to build the workflows and screens that they specifically needed.”

This flexibility of configuration has proved to be particularly important to Guy’s and St Thomas’. They have taken out a maintenance contract and staff have attended both configuration and report generation training courses so that they can make their own adjustments to the system in the future, if and when their needs change.

“The beauty of this approach,” concluded Boother, “is not only that the system is future-proofed against changing requirements, but also any changes that they themselves make to the screens will be fully supported by Autoscribe while the maintenance agreement is in place.”

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LIMSLIMS (Laboratory Information Management System) is an informatics software system used to improve the quality assurance and quality control (QA / QC) of data management. LIMS can be a standard for common lab workflows, such as commercial off the shelf systems (COTS), or customized for more specialized lab use. Systems are available for mainframe computers or PC.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.Laboratory ManagementLaboratory management involves overseeing the operations of a lab, ensuring compliance with safety regulations, optimizing workflows, and maintaining equipment. Efficient lab management is key to ensuring accurate results and minimizing downtime. Technologies like laboratory information management systems (LIMS) and automated lab equipment are helping labs streamline operations. Browse our peer-reviewed product directory to find the best laboratory management tools, compare products, read reviews, and get pricing directly from manufacturers.Sample StoragePreserving clinical trial samples to the highest standards is a critical component in maximizing the value of present day and future clinical research. Specialized storage and transportation of these tissue, blood and serum samples reduces the risk of them being damaged or lost.Sample ProcessingSample processing is required to prepare samples prior to analysis. Technologies used for sample processing include homogenizers, grinders, mills and mixers.
Guy’s and St Thomas’ NHS Foundation Trust Update Their Biological Sample Storage Systems