SelectScience
Join Free
Accelerating Science
NewsLife Sciences

Get your free sample: Sera-Xtracta isolation kits for genomic and cell-free DNA

Cytiva

Automatable, magnetic bead-based nucleic acid isolation kits for cell-free DNA and genomic DNA extraction

12 Mar 2020
Charlie Carter
Life Sciences Editor

Product news

With a liquid sample, you only have a limited amount of useful genetic material. Optimizing your process for isolating and recovering nucleic acid will ensure the maximum amount of cell-free DNA from one sample can be recovered.

Sera-Xtracta Cell-Free DNA Kit is designed for the efficient extraction and purification of cell-free DNA (cfDNA) from blood plasma, selecting for cfDNA while minimizing any co-purification of higher molecular weight genomic DNA that may be present. This kit provides:

  • Efficient recovery of small-fragment cfDNA in the size range 50 to 300 bp.
  • Minimal genomic DNA contamination due to active selection of smaller fragments.

Sera-Xtracta Genomic DNA Kit for whole blood delivers high levels of both yield and purity. It uses a simplified protocol minimizing co-purification of RNA and removes the need for RNAse treatment for most applications:

  • High recovery rates: 4 – 8 μg from 200 μL of whole blood.
  • High purity genomic DNA with a purity ratio (A260/A280) greater than 1.7.

The kits are compatible with molecular biology techniques, including NGS, polymerase chain reaction (PCR), quantitative PCR (qPCR), droplet digital PCR (ddPCR) and other amplification and genotyping applications.

Request A Free Sample

Do you use GE Healthcare products in your lab? Write a review today for your chance to win a $400 Amazon Gift Card>>

Links

CytivaCompany website

Tags

PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Magnetic BeadsDNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.GenomicsGenomics is the study of genomes, focusing on the sequencing, analysis, and interpretation of genetic material. It is key in understanding genetic diseases, evolutionary biology, and personalized medicine. Techniques like next-generation sequencing (NGS) are commonly used in genomics research. Browse our peer-reviewed product directory to find the best genomics tools, compare products, check reviews, and get pricing directly from manufacturers.

Related articles

Get your free sample: Sera-Xtracta isolation kits for genomic and cell-free DNA