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Gentel Biosciences Powers Protein Research with New Proteomics Multi-System™

Gentel Biosciences, Inc
19 Feb 2010
Sarah Sarah
Marketing / Sales

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Gentel Biosciences today launched the Gentel Proteomics Multi-System™ providing “scan-to-analysis” functionality for multiplex immunoassays, lysate and antigen arrays as well as Western Blot, ELISA and tissue imaging, delivering multi-application value to researchers worldwide.

Alex Vodenlich, Gentel’s CEO, said of the system, “The Gentel Proteomics Multi-System is a game-changer in terms of functionality and affordability. It allows researchers with minimal proteomics experience or labs with limited budgets to play at a level never seen before. Gentel provides more than just an assay platform with hardware and software. We are enabling a proteomics-application workhorse that delivers reliable, reproducible results, gets you answers, and advances your research. The Proteomics Multi-System truly opens the gateway to proteomics for the non-protein researcher through its flexibility and ease of use.”

The integrated Proteomics Multi-System includes a high-resolution scanner along with a laptop computer preconfigured with image-capture and analysis software capable of data extraction and quantitation. In addition, the system allows the use of Gentel’s flagship APiX™ chromogenic reagents and slides as well as non-fluorescent proteomics products from other leading vendors.

Dr. Harry Partidos, Senior Scientist at Inviragen, Inc., and his research team leverage the Gentel Proteomics Multi-System in the development of their vaccines that protect against emerging infectious diseases. “We needed a fast and easy method for measuring cytokine levels in mouse models and the Gentel Proteomics Multi-System was a great fit for us,” Dr. Partidos said. “Gentel’s kits and system provide us with a quick profile of immune response from our precious, small-volume samples. It’s a very practical way to measure 12 cytokines simultaneously,” stated Partidos.

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Western BlottingWestern blotting equipment is used to transfer and identify specific proteins within a sample, reveal protein modifications, as well as give a semi-quantitative estimation of their concentration. Western blotting equipment includes all apparatus necessary to transfer proteins from gel to membrane and subsequent processing steps. Protein transfer can be performed by electroblotting with wet, semi-dry and dry transfer systems onto nitrocellulose and PVDF membranes. Blocking, washing and labeling of membranes follows, involving buffers, blocking reagents, blotting / incubation trays, labeling reagents, immunoblotting assays, antibodies and conjugates. Automated equipment for these steps is available to accelerate your lab workflow. Finally, detection and imaging of proteins can be conducted using gel documentation and imaging systems. Find the best western blotting equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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