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Genomics, Proteomics and In Vivo Imaging Systems from UVP at AACR

Analytik Jena GmbH+Co. KG
27 Mar 2013

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Visit UVP's booth 902 at AACR in Washington DC to see the wide range of BioImaging Systems for gel, blot and in vivo imaging applications plus ultraviolet and laboratory products.

The iBox® Explorer™2 Imaging Microscope enables brilliant resolution macro to micro technology for fluorescence in vivo animal imaging. The iBox Explorer provides breakthrough advances with dual lighting and software-controlled objectives for imaging of whole animals, tissue margins to individual cells. Stop by UVP's booth to learn about a webinar which discusses In Vivo imaging applications.

The GelMax™ Imager is designed for fast, easy imaging of precast and mini gels. The GelMax accommodates a wide range of precast and mini gels up to 11.5 x 16cm in size. Illuminate, capture and analyze gels with this easy to use system. "The new GelMax precast and mini gel imager allows researchers to quickly achieve brilliant color, picture-perfect, publication-quality images in a small, simple package. With the increasing popularity of precast gels in the lab, the GelMax is the latest in a long line of gel/blot imaging innovations from UVP," reports Alexander Waluszko, Vice President of Marketing and Sales.

The ChemiDoc-It®TS2 Imager enables quick and simple image capture with the touch of the screen. The integrated computer, touch screen and exclusive capture software simplify workflow for imaging of chemiluminescent, fluorescent and colorimetric gels and blots. Users of the system can optimize gel and chemiluminescent blot imaging with the highly sensitive megapixel resolution, cooled CCD camera. View low light samples in the light-tight darkroom which creates an optimum environment for chemiluminescent blots. No film required for chemiluminescent western blot imaging.

UVP will also feature additional BioImaging Systems including the BioSpectrum® 810 Imaging System. Achieve enhanced image capture with the dynamic 8.1 megapixel high resolution and high sensitivity capabilities. Researchers can capture not only fluorescence gel images, they can also be assured of camera sensitivity and efficient ultra-cooled technology, which permits superior capture of chemiluminescent western blots. The GelDoc-It® series imagers are for high resolution gel imaging and analysis. Select from imagers with a built-in computer/touch screen or an external computer/monitor. Perform basic gel documentation with the BioDoc-It® Imaging System, a compact stand-alone unit with built-in touch screen.

UVP manufactures a large selection of ultraviolet products. The UV lamps feature handheld, high intensity, inspection and bench models in portable and wall powered models. Miniature Pen-Ray® Light Sources are available in custom and standard configurations for uses including fluorescence, inspection, analytical and sterilization applications. Ultraviolet products include a large selection of UV transilluminators, UV crosslinkers and UV cabinets plus UV intensity meters for measuring the useful life of a UV source.

Additional UVP products include HEPA/UV PCR hoods and workstations. HEPA systems feature four-stage filter system for eliminating contamination. Precision heated hybridization ovens include the unique HL-2000 HybriLinker features a hybridization oven and UV crosslinker chambers in one unit for maximizing procedures.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Western BlottingWestern blotting equipment is used to transfer and identify specific proteins within a sample, reveal protein modifications, as well as give a semi-quantitative estimation of their concentration. Western blotting equipment includes all apparatus necessary to transfer proteins from gel to membrane and subsequent processing steps. Protein transfer can be performed by electroblotting with wet, semi-dry and dry transfer systems onto nitrocellulose and PVDF membranes. Blocking, washing and labeling of membranes follows, involving buffers, blocking reagents, blotting / incubation trays, labeling reagents, immunoblotting assays, antibodies and conjugates. Automated equipment for these steps is available to accelerate your lab workflow. Finally, detection and imaging of proteins can be conducted using gel documentation and imaging systems. Find the best western blotting equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel ImagingGel imaging captures high-resolution images of electrophoresis gels to analyze DNA, RNA, and proteins. Essential in molecular biology, this technique helps visualize results for accurate quantification and documentation. Discover top imaging systems and compare user-reviewed options in our directory.ImagingImaging techniques are essential for obtaining visual representations of samples to understand structures, processes, and function in biological, chemical, and physical research. These tools range from traditional light microscopy to advanced imaging modalities like MRI and electron microscopy, providing researchers with valuable data for diagnostics, drug discovery, and material analysis. Explore imaging solutions in our peer-reviewed product directory to compare products, check reviews, and get pricing directly from manufacturers.Small Animal ImagingSmall animal imaging is the visualization of living animals, most commonly mice and rats, for research purposes. This non-invasive technique is vital for long-term studies into drugs effects, as well as small animal anatomy and physiology.ChemiluminescenceBlottingAACRThe American Association for Cancer Research (AACR) is a leading organization focused on cancer research and treatment. It provides a platform for scientists, healthcare professionals, and industry leaders to share knowledge and collaborate in the fight against cancer.

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