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GenNext Technologies and NeoProteomics announce an alliance in biomolecular footprinting

GenNext Technologies

Companies team-up to promote the use of protein footprinting technologies, products, and contract research services in biopharmaceutical research and development

16 Jun 2020
Tom Casburn
Associate Editor

Industry news

GenNext Technologies and NeoProteomics have joined forces to advance biomolecular footprinting knowhow and utility in biopharmaceutical and structural biology research. Neo is a world-recognized leader in footprinting software and services for biopharmaceutical and structural biology research. GenNext is the world’s only provider of footprinting instruments, software, and accessories that enable higher order structural analysis in a compact, intuitively simple, benchtop format.

Together, both companies are developing an informative website dedicated to facilitating the rapid exchange of scholarly content and discourse among researchers working in pharmaceutical and biopharmaceutical development as well as structural biological studies. This website will also provide understandable application examples so scientists and decision makers in the field can immediately grasp the impact of protein footprinting upon their research.

As a next step in educating the community, the companies are pleased to announce an upcoming webinar series to disseminate footprinting know-how and highlight its applied value in biopharmaceutical and structural biology research. Five, one-hour information packed webinars are planned to be presented by leaders in the biomolecular footprinting field, including: Professor Mark Chance, Case Western Reserve University, Professor Michael Gross, Washington University, St. Louis, Professor Joshua Sharp, University of Mississippi, and Professor Lisa Jones, University of Maryland Baltimore.

“We are excited to launch this alliance with NeoProteomics,” remarked Scot Weinberger, President and CEO of GenNext Technologies. “In academic studies, footprinting has provided valuable information by exposing monoclonal antibody defects, elucidating biosimilar failure and storage induced defects, and facilitating the study of orthosteric and allosteric drug-target interactions and protein conformational change. Until now, footprinting has been scantly applied in biopharma due to the inherent complexities of the technique and the absence of facile and reliable commercial products. GenNext provides biopharmas with the world’s first dedicated instrumentation and software products for biopharmaceutical higher order structural studies, which exploit the analytical power of biomolecular footprinting.”

“We too are pleased to align with GenNext Technologies to launch and promote this educational platform.” said John Schenkel, Jr., President and CEO of NeoProteomics. “Over the past few years, we’ve worked with our biotechnology clients and collaborators to demonstrate that protein footprinting is a very precise and versatile biophysical technique, which provides highly significant and actionable data. What’s most exciting however, is the introduction of new technologies which make Protein Footprinting much more accessible. We feel very strongly that by utilizing Protein Footprinting, researchers will be better equipped to attack human disease.”

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Molecular Recognition SoftwareMolecular recognition software is widely used to analyze DNA, RNA, proteins and chemicals. The software can be useful for graphical viewing, comparative analyses, high-throughput screening, genomics, proteomics and phylogenetics. Molecular recognition software uses bioinformatics tools and analyses such as BLAST searches and generates structural predictions, 3D structures and sequencing information.Protein CrystallographyProtein crystallization is the process of crystallizing purified proteins for 3D structure analysis by x-ray crystallography. The main methods of protein crystallization include sitting drop, hanging drop and microbatch. It is important to control parameters such as pH, temperature and concentration. Following crystallization, detectors and software are used for data collection and analysis.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.Structural BiologyBiotechnologyBiotechnology is the use of biological processes, organisms, or systems in the production of products and services. It spans a wide range of applications, including healthcare, agriculture, and environmental management. Browse our peer-reviewed product directory to find the best biotechnology tools, compare products, check reviews, and get pricing directly from manufacturers.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.

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GenNext Technologies and NeoProteomics announce an alliance in biomolecular footprinting