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GENEWIZ, Inc. Launches OncoGxOne™ Discovery Cancer Panels

GENEWIZ, Inc.
17 Apr 2013
Sarah Thomas
Associate Editor

Product news

GENEWIZ, Inc., leading global genomics service provider, announced the launch of OncoGxOne™ Discovery cancer panels, proprietary gene panels designed specifically to assay genomic aberrations for all major cancer types.

Designed and developed by experts with the most recent research data available, GENEWIZ OncoGxOne™ Discovery cancer panels are the most comprehensive cancer-specific gene panels on the market, and have the ability to detect all types of genomic aberrations, including point mutations, Indels, gene fusions, and copy number variance (CNV).

"With the launch of OncoGxOne™ Discovery cancer panels, GENEWIZ has the opportunity to drive advancements in cancer research, offering solutions for biomarker discovery, therapeutic target discovery, and novel mutation identification," stated Dr. Guanghui Hu, Vice President of Translational Genomics.

"Using the latest next generation sequencing and bioinformatics technologies, OncoGxOne™ Discovery cancer panels can detect not only low-frequency variations and gene fusions in both exon and intron regions, but also CNV with great accuracy," Hu asserted. "The resulting data has the ability to stratify patients in clinical trials, as well as make a significant impact on personalized cancer treatment."

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.

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GENEWIZ, Inc. Launches OncoGxOne™ Discovery Cancer Panels