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Genetic Analysis enters service agreement with Eurofins ADME BIOANALYSES

Genetic Analysis AS

The first contract research organization to offer the GA-map microbiome test

28 Oct 2021
Ellen Simms
Product and Reviews Editor

Industry news

Genetic Analysis AS (GA), a molecular diagnostics specialist, has announced a service agreement with Eurofins ADME BIOANALYSES, a contract research organization (CRO) providing diverse services to the pharmaceutical industry in the fields of pharmacokinetics, pharmacodynamics and drug metabolism.

There is increasing demand for the inclusion of gut microbiome assessments in clinical trials and clinical trial research. Eurofins ADME BIOANALYSES’ launch of GA-map® Dysbiosis Test, a CE marked standardized gut microbiome test by Eurofins ADME BIOANALYSES will enhance its comprehensive microbiome service offering for its clinical research customers.

Gut microbiome profiling is increasingly required as a surrogate endpoint or exploratory biomarker in clinical trials. This is due both to the impact new pharmaceuticals can have on the microbiome and the fact that the microbiota composition itself may greatly affect the response to treatment. GA provides the first CE-marked and standardized microbiome test to profile and compare an imbalanced microbiota to healthy references. The standardized GA-map Test is based on a pre-determined targets approach (PDT) and is establishing itself as a valuable tool in drug development, clinical research and routine diagnostics.

Ronny Hermansen, CEO, Genetic Analysis comments: “GA is proud to have Eurofins ADME BIOANALYSES as a partner in the clinical research field. To map and unlock the bacteria present in the gut is instrumental for developing better treatment regimes. The GA-map platform will offer a fast turnaround lab testing service with an integrated software algorithm for immediate result presentation”.

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PharmacokineticsMicrobiomeMicrobiome research focuses on the complex communities of microorganisms living in and on humans, animals, plants, and environments. It plays a crucial role in health, disease, and ecological balance. Explore tools and resources for microbiome analysis, including sequencing platforms and bioinformatics software.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.Drug MetabolismDrug metabolism is the enzymatic conversion within the body of pharmaceutical substances into other chemical compounds. The primary site for drug metabolism is the liver.

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