Genedata at SBI2 will Showcase How Genedata Screener Industrializes HCS

Used by the world's leading research organizations, Screener for HCS is the most effective, streamlined decision-making platform for image-based screening.

14 Sept 2015
Lois Manton-O'Byrne, PhD
Executive Editor

Industry news

Genedata, a leading provider of advanced software solutions for drug discovery and life science research, announced it will be among the presenters at the 2nd Annual Society of Biomolecular Imaging and Informatics (SBI2) Meeting. At SBI2's Data Analysis Colloquium, Genedata will discuss Genedata Screener for HCS, the platform that more than half of the Top 25 pharma and leading research institutes rely upon for data analysis of image-based screening.

Genedata will also demonstrate new solution enhancements for HCS in the recently announced Genedata Screener® version 13.0, such as improved image displays and new functionality for multi-parametric feature selection and quality control in an automated, screening-specific workflow. SBI2, a global scientific event for HCS/HCA, will be held at the Joseph B. Martin Conference Center, Harvard Medical School where Genedata will exhibit at Booth #G2 (Sept. 15-17).

HCS is all about images - screener for HCS enables instant access

As the range of assays, instruments, and user groups increases, so does the complexity of high content screening (HCS). For individual researchers and more importantly enterprises, HCS can be a perfect storm of data analysis challenges, requiring scientists to spend costly time on repetitive tasks that do not necessarily drive deep understanding of the relationship between data and biology.

There is a mandate to reduce the time spent on routine tasks so that scientists are free to focus on the science and results of their experiments -- not data handling. To address these issues, organizations and scientists must scale-up and streamline their HCS analysis workflow, aiming for an industrialized approach to data analysis. Supporting the complete data analysis workflow, Genedata Screener industrializes HCS. It offers integrations with most HCS systems and makes HCS an integral part of the enterprise screening workflow, including the required experiment annotations and results upload to the data warehouse.

Leveraging the enhancements in the new Genedata Screener version 13.0, Screener for HCS now includes:

  • optimized usability such as context-specific image displays, at a single click;
  • completely automated analysis from single cells to end results;
  • interactive definition and analysis of cell populations; and
  • advanced statistics and visualizations for feature exploration and reduction.

Furthermore, Genedata Screener customers can now analyze High Throughput Flow Cytometry experiments alongside HCS. New functionality for data processing from Drug Metabolism and Pharmacokinetics (DMPK) screens, as well as enhancements for Thermal Shift, and Surface Plasmon Resonance (SPR) screening experiments are also built into the new Genedata Screener 13.0, which will be released for general availability on October 6, 2015.

"We are very excited about this latest release of Genedata Screener as it is a major milestone in our plan to streamline and automate the complex data analysis process for HCS," said Dr. Othmar Pfannes, CEO of Genedata. "Genedata is highly committed to addressing the rapidly emerging customer requirements for HCS data analysis. Our domain knowledge gained from working with leading high content screening practitioners from around the world coupled with our collaborative business model, allows us to build Screener, making it the de facto standard in screening activities for both small research organizations and large enterprises."

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.High Content ImagingHigh content imaging is a method combining two or more fluorescent microscopy experiments to identify substances that alter a cell’s phenotype in a desired manner. The process is adapted to multi-well plates and both the image acquisition and analysis are automated.ScreeningUsing robotics, data processing and control software, liquid handling devices and sensitive detectors, screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests.Image AnalysisImage analysis involves the extraction of meaningful information from images, often using software to quantify and interpret visual data. It is widely used in cell biology, material science, and diagnostics. Increasingly, AI is being used to streamline image analysis. Explore image analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.
Genedata at SBI2 will Showcase How Genedata Screener Industrializes HCS