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Gene modulation in primary human immune cells: Successful strategies and applications for CRISPRko, RNAi and beyond
6 Nov 2020
Finn Price
Administrator / Office Personnel
Expert insights
In this upcoming SelectScience webinar, immunology expert Dr. Verena Brucklacher-Waldert, Horizon Discovery, will share successful strategies for the manipulation of genes within physiologically relevant human immune cells. A number of case studies will be presented to highlight the techniques used in a variety of applications employed for gene interrogation, including CRISPRko, RNAi and more.
This webinar will discuss:
- How to modulate gene function in primary immune cells
- How gene modulated primary immune cells can be used to identify new targets
- How to uncover mechanisms of action or use primary immune cells as a therapeutic tool
Who should attend?
- Researchers carrying out gene editing/modulation
- Pharma researchers involved in immunotherapy discovery
The live webinar takes place on Friday, November 20, at:
- 15:00 GMT
- 16:00 CET
- 07:00 PST
- 10:00 EST
SelectScience runs 10+ webinars a month across various scientific topics, discover more of our upcoming webinars>>
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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.RNAiGene EditingGene editing is the precise alteration to an organism's DNA, with CRISPR being the most well-known technique. It is used in a wide range of applications, including the development of disease models and gene therapy, and crop improvement. Browse our peer-reviewed product directory to find the best gene editing solutions, compare products, check reviews, and get pricing directly from manufacturers.ImmunotherapyImmunotherapy is a treatment approach that utilizes the body�s immune system to fight diseases, especially cancer. It includes therapies such as monoclonal antibodies, checkpoint inhibitors, and CAR-T cell therapy. Immunotherapy is a rapidly growing area of research in oncology and autoimmune diseases. Browse our peer-reviewed product directory to find the best immunotherapy tools, compare products, check reviews, and get pricing directly from manufacturers.CRISPRCRISPR technology enables precise editing of genes, allowing scientists to modify DNA at specific locations. This revolutionary tool is used in genetic research, drug development, and gene therapy. CRISPR has applications in agriculture, disease treatment, and creating genetically modified organisms (GMOs). Explore CRISPR solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.