GE Healthcare Launches ÄKTA™ Pure, A New Modular Chromatography System For Protein Purification

28 Aug 2012

Product news

GE Healthcare, the healthcare business of GE announced recently the launch of ÄKTA™ pure, a chromatography system for flexible, reliable and intuitive purification of proteins. ÄKTA pure, the latest addition to the industry-leading ÄKTA range of chromatography systems, is an easy-to-use modular system that offers the flexibility to support both routine and challenging purification requirements, as well as being adaptable to changing research needs.

Johan von Heijne, Head of Research Products, GE Healthcare Life Sciences, said, “In an increasingly challenging research environment, where needs and priorities can change rapidly, researchers want to know that the protein purification system they purchase has longevity. By taking a modular approach with ÄKTA pure, we are providing a system that not only simplifies researchers’ work but also gives them a flexible option for expanding and tailoring their purification capabilities as their research progresses. There is simply an ÄKTA pure for everyone. ”

In today’s research environment, scientists are often expected to undertake all aspects of the protein discovery workflow, from genomics through to purification and characterisation, and the requirement to isolate specific proteins at high purity in short timelines often means that chromatography conditions and methodologies have become more challenging. ÄKTA pure is specifically designed to enable researchers - from beginners to experts - to easily isolate their target protein, whether under simple or complex conditions.

ÄKTA pure eliminates the need for programming skills to control the chromatography run, with the addition of simple drag-and-drop method templates in the UNICORN™ 6 control software. Through the software it is also possible to electronically track the use of, and data obtained from, individual columns, which is particularly useful as chromatography systems are often placed in shared facilities.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Size Exclusion ChromatographySize exclusion chromatography (SEC) is a liquid chromatographic technique used to separate and identify molecules based on their size, including polymers, proteins, nanoparticles & nucleic acid. SEC is further subdivided into gel filtration chromatography (GFC) and gel permeation chromatography (GPC) when an aqueous or organic mobile phase is used respectively. HPLC-based SEC systems and columns are available for analytical separation alongside SEC spin columns or filters to prep samples for many protocols. Find the best size exclusion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PurificationPurification techniques are essential for isolating compounds of interest from complex mixtures, such as proteins, nucleic acids, and chemicals. These techniques are critical in biochemistry, drug development, and environmental studies. Explore purification systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
GE Healthcare Launches ÄKTA™ Pure, A New Modular Chromatography System For Protein Purification