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GE Healthcare introduces Vivaspin™ sample concentrators for protein sample prep

Cytiva
1 May 2008

Product news

GE Healthcare announced today that it is introducing Vivaspin™ sample concentrators for protein sample prep, offering fast and convenient concentration of biological samples with minimal membrane blocking, excellent recoveries (typically >95%) and no risk of concentration to dryness.

Vivaspin provides fast, nondenaturing concentration of up to 30 times from a range of volumes between 100 μl to 20 ml. Sample concentration using Vivaspin is performed by membrane filtration in a single tube and the molecular weight cut-off of the membrane can be selected by the user. The sample is placed into the upper compartment of the tube, and centrifugation is applied to force solvent through a semipermeable membrane into the lower compartment of the tube. This leaves a more concentrated sample in the upper chamber.

Vivaspin is a well established product on the market from Sartorius Stedim Biotech GmbH that will now also be sold under the GE Healthcare brand. Vivaspin represents the latest addition to GE Healthcare’s Trap platform which addresses the need for easy, small-scale preparation of protein samples prior to analyses such as 1-D, 2-D, MS and LC-MS.

The new Vivaspin sample concentrators are available now from GE Healthcare.

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ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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GE Healthcare introduces Vivaspin™ sample concentrators for protein sample prep