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GCMS-TQ8050 Triple Quadrupole GC-MS: One of the Highest Sensitivity Levels Worldwide

Shimadzu Corporation

Quantitation with higher accuracy and reliability than ever before

31 Aug 2016
Finn Price
Administrator / Office Personnel

Product news

Shimadzu has released the GCMS-TQ8050 Triple Quadrupole GC-MS. This ultra-high-sensitivity GC-MS/MS system offers both robustness and one of the highest sensitivity levels in the world.

In addition to detecting ultra-trace concentrations of components down to femtogram level, it can also maintain those ultra-high sensitivity levels for long periods. This makes it an ideal GC-MS/MS system for applications requiring ultra-trace analysis, such as analyzing ultra-trace concentrations of persistent organic pollutants (POPs) or endocrine-disrupting chemicals in the environment or analyzing impurities in pharmaceuticals.

Background to development

After introducing the GCMS-TQ8030 triple quadrupole gas chromatograph mass spectrometer in 2012, Shimadzu introduced the GCMS-TQ8040 in 2014, which featured improved operability. All over the world, this was especially well received in fields such as residual pesticide analysis, forensic toxicology, and metabolite analysis.

With the increasing sensitivity available in GC-MS/MS systems, the range of applications needing systems capable of femtogram-level quantitative analysis is expanding world-wide. In Europe, for example, high-resolution GC-MS systems were almost exclusively used to analyze dioxins and polychlorinated biphenyls (PCBs) in foods and animal feed but in 2014 GC-MS/MS was also added as a method for confirmation analysis.

By adding this newly developed top-of-the-line GCMS-TQ8050 system to the product range, Shimadzu will offer new solutions not only for existing customers but also other testing laboratories requiring even more sensitive ultra-high sensitivity analysis.

One of the world's highest sensitivity levels

In addition to using an ultra-high-sensitivity detector that can detect femtogram-level concentrations, the GCMS-TQ8050 also features newly developed noise reduction technologies which help achieve the world's highest sensitivity levels (2.5 times higher signal-to-noise ratio than the previous model). This exceptional performance means dioxins and endocrine disrupting chemicals in foods, for example, can be quantitated with higher accuracy and reliability than ever before.

Maintaining ultra-high sensitivity five times longer

Furthermore, if the previous detector is used to detect compounds at femtogram-level, the detector gain has to be set so high that it causes a premature deterioration of the detector. In contrast, the new detector can be used for femtogram-level ultra-trace analysis without applying undue loads on the detector. That makes premature deterioration unlikely and results in the new detector maintaining ultra-high sensitivity five times longer than the previous detector. In addition, robustness as a GC-MS/MS system has been improved and maintenance frequency and costs have been reduced significantly by including features such as a highly stable ion source with patented technology and a quadrupole equipped with pre-rods.

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Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Triple Quadrupole MsChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.Trace Level ImpuritiesTrace level impurities refer to low concentrations of unwanted substances found in chemicals, pharmaceuticals, and other products. Detecting and removing these impurities is crucial for product safety and regulatory compliance. Explore trace impurity analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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GCMS-TQ8050 Triple Quadrupole GC-MS: One of the Highest Sensitivity Levels Worldwide