Free Webinar: Using Patient-Derived 3D Cell Culture Models for Semi-Automated Drug Screening

Learn how you can advance pre-clinical development of novel anti-cancer compounds

10 Oct 2017
Sarah Thomas
Associate Editor

Expert insights

Personalized oncology is revolutionizing patient care. In a SelectScience® webinar, Dr. Christian Regenbrecht, Founder and CEO, Cellular Phenomics & Oncology (CPO), will discuss how comprehensive patient-derived 3D cell culture models can be integrated into the pre-clinical development of novel anti-cancer compounds.

Registration is now open for the event which will explore the benefits of using these cell cultures instead of adherent 2D cell as well as current limitations. Regenbrecht will present a prototypic workflow and explain a semi-automated set-up for high-throughput screening (HTS) and several case studies that demonstrate how patient-derived cell culture models can be used in personalized oncology. You'll also have the chance to ask any questions you may have during the Q&A session.

Who should attend?

Scientists from pharma, biotech and academia who work in the field of pre-clinical drug development. Decision makers who want to explore opportunities to reduce the use of animal models. Oncologists who want to be informed about how this will transform future patient care.

Register now for the event which will take place on October 23, 2017 at 15:00 BST / 10:00 EDT / 07:00 PDT / 16:00 CEST. If you cannot attend the live event, please register to watch the webinar in your own time.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Compound ScreeningCompound screening is a method used to discover specific compounds that could be promising candidates for pharmaceutical use. This potential is identified when compounds interact with the target protein during screening and could therefore be carried forward in the drug development process.Phenotypic ScreeningPhenotypic screening assesses cellular responses to compounds, enabling drug discovery and target identification. This technique is pivotal in finding effective treatments for complex diseases. Discover phenotypic screening platforms and tools with peer-reviewed comparisons and pricing in our directory.
Free Webinar: Using Patient-Derived 3D Cell Culture Models for Semi-Automated Drug Screening