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Free Webinar: Label-Free High-Throughput MALDI TOF Mass Spectrometry in Drug Discovery

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Learn how ultra-fast MALDI mass spectrometry can be used for high and ultra-throughput screening

6 Nov 2017
Finn Price
Administrator / Office Personnel

Expert insights

Matrix assisted laser desorption/ionization time of flight (MALDI TOF) mass spectrometry is a technique commonly used for a variety of applications from proteomics to drug discovery. Register for this webinar presented by Matthias Trost, Professor of Proteomics at Newcastle University, to learn more about the technique and the benefits of label-free screening approaches compared to current labeled approaches. The data presented will focus on enzymes in the ubiquitin system (deubiquitylases, E2/E3 ligases) and protein kinases.

Registration is now open for the live event that will be held on Monday, November 20. Don’t worry if you can’t attend, register anyway and we will send you a link to watch the webinar on demand at a time that’s convenient for you.

Watch this webinar to learn:

  • The basics of MALDI TOF mass spectrometry
  • The benefit of label-free screening compared to current labeled approaches
  • How ultra-fast MALDI mass spectrometry can be used for high and ultra-throughput screening

This webinar is ideal for anyone involved in drug discovery and screening; pharma, biotech, CROs and academia. We also recommend this presentation for mass spectrometrists planning to use MALDI TOF, or non-mass spectrometric experts intending to move from labeled to label-free techniques.

The webinar will take place on Monday, November 20, 2017 at:

  • 16:00 GMT
  • 17:00 CET
  • 11:00 EST
  • 08:00 PST

Don’t forget, if you can’t attend the live event, register now to receive a link to watch the webinar on demand when it’s convenient for you.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MALDI-TOF MSMALDI-TOF mass spectrometers (matrix-assisted laser desorption/ionization time-of-flight) are used for the mass analysis of large molecules, including proteins, DNA, polymers and other macromolecules due to its relatively soft ionization, reducing fragmentation whilst allowing fast data acquisition. Tandem mass analyzers such as TOF/TOF systems can be used to increase resolution and sensitivity of your analysis. Find the best MALDI-TOF products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.Label-Free AnalysisScreeningUsing robotics, data processing and control software, liquid handling devices and sensitive detectors, screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests.

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