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Free SelectScience Webinar: Technology Accelerating Biopharma: Complete Workflow Solutions in Biopharmaceutical Discovery and Development

SelectScience
3 Nov 2015
Lois Manton-O'Byrne, PhD
Executive Editor

Expert insights

Protein biopharmaceuticals are being developed at an explosive rate and have attracted great interest from both smaller biotech firms and big pharma. But discovery and development of biopharmaceuticals is difficult. There are many challenges, and scientists must not only stay abreast of advances in knowledge and improvements in technology, but also navigate the maze of shifting government regulations. Making good decisions fast is critical.

In this two-day webinar event series, guest speakers will discuss:

  • An automated, turn-key sample prep platform for biopharmaceutical characterization and quantification.
  • How to assign peaks and structures in HILIC FLR analysis of released N-glycans.
  • How to enable mass measurement from bioseparations: A HIC/RP multiple heart-cutting 2D-LC/MS platform.
  • LC/MS workflows for biosimilars and antibody drug conjugates.
  • Solutions for the core and protein laboratory using MassHunter Walkup Software.
  • Benefits of adding ion mobility to LC/Q-TOF/MS.
  • Biopharma workflows using the MassHunter BioConfirm tool.

Featured Topics and Speakers:

Part One: LC/MS Workflows for Biosimilars & Antibody Drug Conjugates

Caroline Chu, PhD, Applications Scientist, Agilent Technologies

Solutions for the Core and Protein Laboratory: MassHunter Walkup

Jade Byrd, MassHunter Product Manager, Agilent Technologies

Part Two: Native Protein Characterization Using the Agilent 6560 Ion Mobility Q-TOF

David Wong, PhD, Sr Applications Scientist, Agilent Technologies

Enhanced Software Tools for Biopharma Analysis

Steve Madden, Bioconfirm Software Product Manager, Agilent Technologies

Part Three: Automated Sample Prep for Biopharmaceutical Analysis

Randy Bolger, PhD, Manager of Workflow Solutions, Agilent Technologies

Part Four: Identifying Released Glycans in a HILIC-FLR-MS Workflow Using Free Software Tools

Oscar Potter, PhD, R&D Scientist, Agilent Technologies

Enabling Mass Measurement from Bioseparations: A HIC/RP Multiple Heart-cutting 2D- LC/MS Platform

Greg Staples, PhD, Research Scientist, Agilent Technologies

Parts One and Two of the webinar will take place from 11:00 EST/08:00 PST/16:00 GMT/17:00 CET on November 5 and Parts Three and Four will take place from 12:00 EST/09:00 PST/17:00 GMT/18:00 CET on November 12. All presentations will be available on-demand if you are unable to attend the live event.

Register today for your free place!

Related products

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6560 Ion Mobility Q-TOF LC/MS

Agilent Technologies

The NEW Agilent 6560C ion mobility Q-TOF LC/MS system delivers unrivaled separation and selectivity by combining chromatography, ion mobility, and mass spectrometry. The 6560C Q-TOF LC/MS can even uncover structural information that cannot be seen with traditional LC/MS systems, including separation of in-class isomers via high-resolution demultiplexing (HRdm).

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MassHunter Workstation Software

Agilent Technologies

Making MS operation easierfrom tuning to final report      The all new Agilent MassHunter Workstation software provides intuitive, yet powerful, instrument control, data acquisition, qualitative and quantitative data analysis, and reporting for Agilent time-of-flight (TOF), quadrupole time-of-flight (Q-TOF), ICP-MS, and triple quadrupole systems. Designed from the ground up to make MS analyses easierfrom tuning to final reportMassHunter Workstation software can be complemented by application-specific MassHunter software packages that provide even more power and stream-lined operation for specialized analytical tasks such as expression profiling.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.GlycansAutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.BiosimilarsBiosimilars are very similar versions of approved and authorized medicines. Clinically inactive components will have minor differences, but there are no significant differences between the biosimilar and the original product in terms of potency, purity and safety.Antibody Drug ConjugatesProtein Quantification

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