SelectScience
Join Free
Accelerating Science
NewsSeparations

Free SelectScience Webinar: Raise Your Nano LC-MS Performance with New Thermo Scientific Solutions

SelectScience

Register your place for this exciting event and Q&A session!

25 Jan 2016
Lois Manton-O'Byrne, PhD
Executive Editor

Expert insights

Nano liquid chromatography (LC) is a powerful tool for discovery and validation studies in LC-MS proteomics. It provides very high sensitivity and a wide dynamic range, which are essential to confidently analyze complex biological samples. Recent technological advances bring a high level of nano LC robustness and performance that are required to overcome analytical challenges and increase analytical throughput.

In this webinar, Dr. Alexander Boychenko and Dr. Stephan Meding, LC-MS Application Specialists at Thermo Fisher Scientific, will discuss the latest innovations in nano LC-MS technology.

By watching this webinar, you will discover:

  • A set of standard and advanced LC-MS applications that can be successfully performed on new nano LC systems in combination with high-resolution mass spectrometers
  • How to overcome major challenges in nano LC-MS analyses of complex samples

The Q&A session during the webinar will give you the opportunity to ask any questions you may have for Alexander and Stephan.

The webinar will take place at 08:00 PST / 11:00 EST / 16:00 GMT / 17:00 CET February 8, 2016, and will be available on-demand if you are unable to attend the live event.

Register today for your free place.

Links

SelectScienceCompany website

Tags

LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.NanoLCNano LC is a nano scale liquid chromatography technique typically used for proteomic applications. The nano refers to the very low flow rate of the mobile phase in the system. The advantage of nanoLC is its high sensitivity. Often the system is integrated with a mass spectrometer in nano LC-MS or nano LC-MS/MS. When using nanoLC equipment consider column choice, software and accurate and precise flow rate control.High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.Method ValidationMethod validation is the process used to prove that the analytical procedure used for a particular test is capable of providing suitable data.LC-MSLiquid Chromatography-Mass Spectrometry (LCMS) is a powerful analytical technique that combines the separation power of liquid chromatography with the detection capabilities of mass spectrometry. It is widely used for qualitative and quantitative analysis of complex mixtures in pharmaceuticals, proteomics, and environmental studies. Browse our peer-reviewed product directory to find the best LCMS systems, compare products, check reviews, and get pricing directly from manufacturers.

Related articles