Four-Channel HPLC Increases Clinical Throughput Capabilities with Class I Medical Device Listing

Bringing the advantages of high-throughput HPLC to the clinical market

28 Jul 2015
Chelsie Phillips
Temporary Editorial Assistant

Product news

Thermo Fisher Scientific’s new four-channel, high-performance liquid chromatography (HPLC) system is designed to increase productivity and efficiency of clinical sample preparations, while freeing valuable bench space; perfect for clinical laboratories requiring high-throughput separations for their LC-MS assays. Listed with the FDA as a Class I medical device for general clinical use, the Thermo Scientific Prelude LX-4 MD HPLC quadruples the productivity of a single-channel HPLC using four parallel channels that deliver up to four separations in a single instrument, streamlining LC-MS workflows and reducing mass spectrometer idle time. The four channels can run identical or different LC-MS assays simultaneously, which provides flexibility for varying clinical separations and maximizes mass spectrometer utilization.

"We are strongly committed to bringing the advantages of LC-MS to the clinical market,” said Bradley Hart, director of market development for Thermo Fisher Scientific. “The Prelude LX-4 MD is one of the first products within a broader initiative to make sample separations and mass spectrometry more useful and accessible to the clinician.”

The Prelude LX-4 MD is the newest addition to the family of Thermo Scientific chromatography and mass spectrometry instruments and software for the clinical lab, which includes the Thermo Scientific Endura MD triple quadrupole mass spectrometer, Prelude MD HPLC and ClinQuan MD software, designed for clinical analyses of patient samples. The Prelude LX-4 MD HPLC will be exhibited at the American Association for Clinical Chemistry Annual Meeting & Clinical Lab Expo, Booth 3135 at the Georgia World Congress Center, Atlanta, GA.

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HematologyIn Haematology / Hematology, complete blood cell counts (or full blood counts) are obtained using automated blood count analyzers to enumerate blood cell types.  Hematology also encompasses haemostasis and coagulation, thrombophilia and hemophilia, plasma viscosity and ESR analysis, hemoglobinopathies, cell morphology and haematinic measurement.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AACCThe American Association for Clinical Chemistry (AACC) Annual Meeting and Clinical Lab Expo is the largest meeting for clinical laboratory professionals in the world. This year's meeting is being held in Atlanta, USA, July 26th-30th, 2015.Protein SeparationClinical StudyProspective biomedical or behavioral research studies on human subjects, following tests in animals, that are designed to answer specific questions about novel vaccines, drugs, treatments, dietary supplements, devices or new ways of using known interventions, generating safety and efficacy data.Clinical Mass SpectrometryMass spectrometry is emerging as a superior method of analysis over the longstanding, gold standard of immunoassay. Clinical mass spectrometry systems are increasingly accessible to medical laboratories and are capable of providing results with more speed and less expense than traditional methods. From simple mass spectrometers to IVDR class A compliant, highly sophisticated systems performing liquid chromatography tandem mass spectrometry (LC/MS/MS), find the latest product news, reviews and resources to make a purchasing decision for your laboratory.
Four-Channel HPLC Increases Clinical Throughput Capabilities with Class I Medical Device Listing