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Find out how you can robustly quantitate monoclonal antibodies from a biological matrix
Discover an optimized, integrated workflow in our upcoming webinar for biopharmaceutical and biotech scientists
11 Aug 2019
Sarah Thomas
Associate Editor
Expert insights
In an upcoming SelectScience webinar, on August 27, 2019, Dr. David Wong and Dr. Yanan Yang discuss a highly sensitive and automated workflow solution for quantitating intact monoclonal antibodies (mAb) from a biological matrix, as well as:
- Optimized workflow solutions ranging from sample preparation and separation to data acquisition and analysis
- High-throughput and reproducible methods for the simultaneous quantitation of various mixtures of mAbs using limited sample prep
- Robust workflows with an excellent dynamic range of over three orders of magnitude and low picogram sensitivity.
Attend this webinar to learn how to:
- Prepare samples using the highly automated AssayMAP Bravo liquid-handling platform
- Optimize HPLC methods using PLRP-S columns for higher column temperature stability and high flow rates and enable better MS sensitivity and reproducibility
- Achieve the best sensitivity using the 6545XT AdvanceBio LC/Q-TOF system for intact mAb analysis
- Set up various data processing methods for accurate intact mAb quantitative analysis.
After the presentation, you’ll also have the chance to put your questions to our speakers during a Q&A session.
REGISTER NOWWho should attend:
- Primarily scientists working in the biopharmaceutical and biotech sectors.
The live webinar takes place on Tuesday, August 27, 2019, at:
- 16:00 BST
- 11:00 EDT
- 08:00 PDT
- 17:00 CEST
Scheduling conflict? No matter, register to receive an on-demand link to watch later>>
For Research Use Only. Not for use in diagnostic procedures.
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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Monoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.BiotechnologyBiotechnology is the use of biological processes, organisms, or systems in the production of products and services. It spans a wide range of applications, including healthcare, agriculture, and environmental management. Browse our peer-reviewed product directory to find the best biotechnology tools, compare products, check reviews, and get pricing directly from manufacturers.Engineered AntibodiesEngineered antibodies are modified to enhance specificity, stability, and functionality for therapeutic and diagnostic applications. These antibodies are central to immunotherapy and biomarker detection. Compare engineered antibody solutions in our directory to find top products and reviews.