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Fighting Antimicrobial Resistance with Enhanced Microbiology Testing

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Find out how LGC provides a range of specialist microbiology services to support the discovery and development of antimicrobials

27 Jan 2017
Lucy Vass
Administrator / Office Personnel

Editorial article

Theresa Wilson, a scientist within Drug Development Services at LGC

We hope to work with clients to assist with novel compound development and help with the fight against antibiotic resistance

Theresa Wilson,  


Drug Development Services, LGC

Theresa Wilson, a scientist within Drug Development Services at LGC, explained the range microbial testing services that are provided by LGC. These include Microbiology Services, which provide antibiotics testing and novel compound testing to identify lead compounds.

Theresa, who uses MALDI-TOF (matrix-assisted laser desorption/ionization time of flight) for identification of bacterial isolates, highlighted that the system used provides an enhanced library to improve the accuracy of identification. She also notes that using MALDI-TOF "improves workflow by using enhanced working methods compared to traditional biochemical techniques".

Theresa continued to explain how the Microbiology Testing Service can help assist drug development by providing a number of antimicrobial activities. She says "It's our role to guide [the client] on antimicrobial activity and any resistance potential".

Watch the full interview here and visit LGC’s company profile to find out more about its services.

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MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MALDI-TOF MSMALDI-TOF mass spectrometers (matrix-assisted laser desorption/ionization time-of-flight) are used for the mass analysis of large molecules, including proteins, DNA, polymers and other macromolecules due to its relatively soft ionization, reducing fragmentation whilst allowing fast data acquisition. Tandem mass analyzers such as TOF/TOF systems can be used to increase resolution and sensitivity of your analysis. Find the best MALDI-TOF products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AntimicrobialsMicrobial DetectionMicrobial detection is crucial for identifying and quantifying bacteria, viruses, fungi, and other microorganisms. This process is essential for food safety, environmental monitoring, clinical diagnostics, and pharmaceutical manufacturing. Explore the best microbial detection tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.AntibioticsAntibiotics are substances that kill or inhibit the growth of microorganisms, such as bacteria and fungi. They are essential in the treatment of infections and in preventing disease spread. Explore antibiotics research and diagnostic tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Antibiotic ResistanceAntibiotic resistance poses a significant threat to public health driving innovation and change through antibiotic stewardship efforts. Ongoing research and diagnostic efforts focus on new treatments and detection methods. Explore antibiotic resistance research and diagnostic tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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