febit and TGen Collaborate to Study New DNA Capture Method

14 Aug 2008

Product news

febit and the Translational Genomics Research Institute (TGen) today announced the formation of a collaboration in which TGen will evaluate Next-Generation-Sequencing equipment in conjunction with febit’s proprietary Geniom® Microarray Technology.

febit’s HybSelect™ Technology enables selective DNA capture and elution, an extremely efficient method to preselect sequences for Next-Generation Sequencers. HybSelect is based on febit’s proven Geniom Technology and uses arrays within microfludic biochips for the selection process of targeted DNA. Geniom biochips are programmable and can contain any desired set of capture probes. The new method combines the extraordinary performance of latest sequencers with the efficient selection capabilities of Geniom Technology.

“We are delighted to have TGen as our first U.S. pilot user of HybSelect with the latest sequencing instrumentation,” said Cord F. Staehler, president of febit. “We will obtain important data from TGen that will help us as we prepare for the official introduction of HybSelect in early 2009.”

The collaboration provides TGen scientists pre-market access to a highly developed DNA capturing method.

“There’s been a great deal of conversation on the future direction of genomic research centers on next generation sequencing,” said Matthew Huentelman, Ph.D., TGen associate investigator and lead collaborator on this project. “This collaboration on the use and further development of this method enhances the opportunities for TGen researchers to make a difference in research utilizing next generation sequencing.”

TGen has been a user of the Geniom One device for the production and microarray analysis of Geniom Biochips since 2006.

Links

Tags

Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.