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Fast Triple Quadrupole Mass Spectrometer from Shimadzu

8 Nov 2010
Sarah Sarah
Marketing / Sales

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The LCMS-8030 from Shimadzu combines the power of triple quadrupole mass spectrometry with unmatched speed to provide the ideal complement to its UHPLC systems. It allows researchers to detect more target analytes with greater sensitivity in hundreds of samples per day and accelerates workflows for high-throughput analysis. It is also suitable for various industries such as pharmaceutical, environmental, chemical and food.

The LCMS-8030 features ultra-fast multiple reaction monitoring (MRM) transitions, enabling data acquisition with up to 500 different channels per second. The improvements to the electronics provide ultra-fast mass spectrum measurement speeds of 15,000 u/sec without sacrificing sensitivity or resolution, with ultra-fast polarity switching (15 msec) for maximum information without signal deterioration.

Highly reliable results
Patented UFsweeper technology accelerates ions out of the collision cell by forming a pseudo-potential surface. The result is high-efficiency collision-induced dissociation (CID) and ultra-fast ion transport, reducing sensitivity losses and cross talk observed on other systems. In addition, higher radio frequency (RF) power capability minimizes pauses between each transition.

When coupled with Shimadzu’s Nexera UHPLC, the LCMS-8030 can provide reliable and accurate detection of peaks just one-second wide, thereby maximizing UHPLC performance. With a polarity switching time of just 15 ms, ultra-fast triple quadrupole measurement time is now a reality.

Seamless LC/MS/MS analyses
The combination of the LCMS-8030 with the class-leading Nexera UHPLC brings the latest hardware together on one platform. This unified platform provides unmatched qualitative and quantitative analysis, increased productivity and accelerated workflows for high-throughput analysis. Automated optimization of analytical conditions for each quantitative target compound, which is the key to high-sensitivity analysis, allows unattended, overnight operation. In addition, all software operations are handled seamlessly, reducing PC conflicts and the need for user intervention.

With the LCMS-8030, maintenance has never been easier or more accessible. Its robust design allows maximum uptime, resulting in a system that can handle most complex matrices. Maintenance of the desolvation line without breaking vacuum minimizes instrument downtime.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.

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