Fantastic Fluorescence for Clinical Microbiology

Clear, bright broad spectrum illumination – without the mercury!

7 May 2015
Lauren Edwards
Editorial

Product news

There’s now a better and safer alternative to a high-pressure mercury or metal-halide light source for fluorescence microscopy. Available from Alpha Laboratories, the pE-300white unit from CoolLED offers broad spectrum LED illumination for general use in fluorescence applications. With a comprehensive range of microscope adaptors, it can easily be fitted to most microscopes, old or new, providing a safe, convenient and economical illumination system that will last for many years without additional operating costs.

Directly replacing a mercury or metal halide lamp the pE-300white has a spectral coverage from the UV (DAPI excitation) to the Red region (Cy5 excitation). The illumination system will excite common fluorophores used in clinical and research laboratory environments. It has a long lifetime (25,000 hours) and no alignment or bulb replacement is required. The instant on/off means no warm up is needed.

The pE-300white is ideally suited for use with the AdvanDx QuickFISH™ assays, also available from Alpha Laboratories. These assays enable rapid identification of pathogen species from blood culture in just 20 minutes. Using a simple fluorescent slide based procedure they can play a critical role in improving patient outcomes by helping to identify the best antibiotic to use in sepsis cases. More targeted antibiotic therapy also helps control costs and reduce the prevalence of drug resistance.

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Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Fluorescence MicroscopyFluorescence microscopy has become an essential tool in biology, as well as in materials science. The application of many fluorochromes has made it possible to identify cells and sub-microscopic cellular components with a high degree of specificity. Using multiple fluorescence labels, different probes can simultaneously identify several target molecules.
Fantastic Fluorescence for Clinical Microbiology