Expanding Accessibility to High-Resolution MS Data with the First SmartMS-Enabled LC-MS Biopharma System

As the number of analytical monitoring tests for biopharmaceuticals skyrockets, Waters builds intelligence into a new LC-MS biopharma system

15 May 2019
Emily Adam
Publishing / Media

Industry news

Waters Corporation has introduced the BioAccord™ System, a purposefully designed liquid chromatography-mass spectrometry (LC-MS) solution that will expand access to high-resolution time-of-flight mass spectrometry capabilities to more scientists. The BioAccord System promises to move routine monitoring out of centralized MS labs and into the hands of more scientists by enabling more effective analysis of biotherapeutic protein attributes across development and within quality control organizations.


"The pace of innovation in the biopharmaceutical industry is accelerating, and with it, the monitoring requirements for biotherapeutics are growing exponentially," said Chris O'Connell, Chairman and CEO, Waters Corporation. "The inherent complexity of these therapies, combined with rising regulatory standards, are driving more intensive and widespread testing requirements. Waters designed the BioAccord System as a fit-for-purpose LC-MS biopharmaceutical solution to deliver rich mass spectrometry data for improved productivity and effective decision-making."

The BioAccord System pairs ACQUITY™ UPLC™ I-Class Plus with the newly-developed ACQUITY RDa™ Detector featuring SmartMS™. This system offers new levels of user experience, with automated setup and self-diagnosis delivered through an intuitive user interface, all within a surprisingly small footprint. Powered by UNIFI™, Waters’ compliance-ready LC-MS informatics platform, the BioAccord System has been optimized for intact protein, released glycan, and peptide monitoring applications, and streamlined by the use of Waters' application-specific chemistries and consumables kits.

The BioAccord will be showcased at the American Society for Mass Spectrometry’s (ASMS) Annual Meeting in Atlanta, Georgia, USA, from June 2-6, 2019.

Learn more about Waters' events at ASMS 2019, and register, here.

BioAccord LC-MS System

Waters

The First SmartMS-Enabled Biopharma Solution  The Waters BioAccord System is an integrated system that simplifies high performance LC-MS biopharmaceutical analysis for every user. An easy-to-use system solution that puts the power to make decisions directly in your hands; a self-calibrating, self-optimizing, self-sufficient tool that equips you with high quality data you can use to tackle the challenges you face every day during biopharmaceutical development.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.ASMSThe American Society for Mass Spectrometry (ASMS) is an organization dedicated to advancing the science and application of mass spectrometry. ASMS supports professionals through events, publications, and research initiatives, promoting innovation in areas like proteomics, metabolomics, and environmental analysis.