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Exclusive Liquid Biopsy Video Interviews

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Hear from experts in the field on the revolutionary technique of liquid biopsies

20 Sept 2016
Sonia Nicholas
Managing Editor and Clinical Lead

Editorial article

Liquid biopsies test fluid samples for cancer biomarkers, such as cell-free circulating DNA


SelectScience® is currently running a fascinating Liquid Biopsy Special Feature. Visit the feature to find liquid biopsy related news, exclusive editorial articles, videos and downloads. This article contains a round-up of exclusive video interviews with leading experts in the field of liquid biopsies. Watch the videos to learn more about Droplet Digital PCR, prenatal testing, emerging biomarkers and new methods.

1. Using Droplet Digital™ PCR for Cancer and Liquid Biopsy Studies

 

In this video webinar from Bio-Rad, you can listen to Dr Dawne Shelton describe how Droplet Digital PCR technology is being used to identify cancer subtypes, optimize drug treatment plans, monitor residual disease and study tumor evolution. Droplet Digital PCR assays offer advantages in liquid biopsies by enabling the measurement of circulating nucleic acid and circulating tumor cells in blood.

2. LifeCodexx Partners with Qiagen to Improve the PrenaTest, Europe’s First Non-invasive Prenatal Test

 

In this video, Dr Stephan Busche, Laboratory Head at LifeCodexx AG, explains how protocols and kits from QIAGEN have made a pioneering liquid-biopsy based, pre-natal test possible. There is a 1% risk of procedure-related miscarriage, but this innovative method relying on prenatal DNA collected from the mother's blood hopes to remove the need for invasive pre-natal testing.

3. Identifying Cancer Biomarkers from Liquid Biopsies Using Digital PCR

 

David Polsky, MD, PhD, Professor of Dermatologic Oncology at the New York University School of Medicine, reveals breakthroughs in melanoma research and how cancer research is being advanced using cutting-edge digital PCR, to identify novel biomarkers identification from liquid biopsies.

4. Improved Sample Stabilization for Liquid Biopsy Analyses

 

Jodi Alt, PhD, Research and Development Scientific Manager at Streck Inc., introduces Cell-Free DNA Blood Collection Tubes and Cell-Free DNA Urine Preserve for enhanced stabilization of liquid biopsy samples for downstream analyses, including PCR and NGS.

5. Enhanced Identification & Isolation of Cancer Cells Using Acoustic Technology

 

Dr Bruno Sainz, Ramón y Cajal Investigator at Autónoma University of Madrid, explains how his cancer research has been facilitated by acoustic based flow cytometry. This technology enables reliable and efficient identification and isolation of cells from tumors and liquid biopsies.

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Cell-Free DNA BCT®

Streck

For In Vitro Diagnostic Use. Cell-Free DNA BCT is a direct-draw venous whole blood collection device intended for the collection, stabilization and transport of venous whole blood samples for use in conjunction with cell-free DNA next generation sequencing assays For that have been cleared or approved for use with samples collected into the Cell-Free DNA BCT device. Performance characteristics of this device have only been established on the Guardant360 CDx assay.

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Streck® Urine Preserve

Streck

Streck Urine Preserve is a ready-to-use liquid reagent that stabilizes nucleic acid targets in urine for up to 7 days at 6 °C to 37 °C to limit changes associated with sample handling, shipping and field collection.  

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PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Liquid BiopsiesLiquid biopsies are non-invasive tests used to detect cancer and other diseases by analyzing blood or other bodily fluids. This technique is gaining popularity for early detection, monitoring treatment response, and detecting minimal residual disease. Explore liquid biopsy solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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