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Excellims Advances Chromatography with New HPIMS-LC System at Pittcon 2013

Excellims
15 Mar 2013
Sarah Thomas
Associate Editor

Product news

Excellims, world innovator in Ion Mobility solutions for chemical detection in industry and research, announces the IA3100, the latest addition to its line of High Performance Ion Mobility (HPIMSTM) Instruments. This game-changing technology will debut at the 2013 Pittcon Conference and Expo Booth No.2007.

High performance ion mobility spectrometry (HPIMSTM) offers high resolution separation based on analytes' gas phase ion mobilities. HPIMS delivers resolving power that complements modern chromatography and mass spectrometry analysis. The IA3100 hyphenated chromatography-ion mobility spectrometer system is used for the most comprehensive analytical separation of complex samples. The benefits of HPIMS are realized through simultaneous separation and detection. Excellims provides standalone and transportableconfigurations with flexible sampling accessories that are a practical solution for laboratory, process and field use.

The superior separation speed and impressive 70+ resolving power of HPIMS make it an ideal tool for high throughput analysis and screening. It can be combined with or used in place of chromatography and mass spectrometry. HPIMS is well suited for applications requiring robust analysis that need to be performed in challenging environments, typically found outside of a lab.
HPIMS provides standalone chemical analysis at lower costs and without added complexity. Excellims GA2100 DirectSprayTM and RA4100 Research HPIMSTM instruments are used throughout the world in government and other organizations identifying contamination and detecting counterfeits in food and drug products.

Dr. Ching Wu, Excellims CEO adds, "The IA3100 brings the power of HPLC and HPIMS together as a complete separation and detection solution. Challenging separations such as isomers will make this combination a first tool of choice. Combining HPIMS with HPLC simplifies complex method development and significantly reduces analysis time. The IA3100 user interface provides seamless operation and data collection. The total solution for isomers separation is now complete and results are displayed in enhanced 3D format".

Applications in pharmaceutical and chemical manufacturing processes include: reaction monitoring, cleaning verification and content uniformity.

In addition, food and drug inspection plus explosives and controlled-substance detection are further applications for the unique capabilities of HPIMS.

Founded in 2005, Excellims Corporation developed the HPIMStechnology to answer the needs of government and industry for better alternatives of detecting chemical substances with speed and accuracy.

Excellims will be showcasing the IA3100 technology, along with its GA2100 and RA4100 family of HPIMS analyzers at Pittcon 2013, Booth No.2007.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Flow ChemistryFlow chemistry describes a chemical reaction being carried out continuously rather than in a batch process. The reagents are pumped through a pipe and forced together at a mixing junction, where they are allowed to combine until the reaction is stopped.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.Ion Mobility Spectrometry

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