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Eppendorf automates cell culture liquid handling within a laminar flow hood

Eppendorf
14 Mar 2008

Product news

Designed to fit inside a laminar flow hood, the epMotion 5070 CB automated liquid handling system from Eppendorf AG offers important advantages for cell biologists. Enhanced safety and fewer pipetting errors are added to the ability to increase the statistical significance of cell culture experiments through the use of higher density formats.

Cell culture liquid handling is usually tedious and time consuming, typically limiting the sample numbers. However, the epMotion 5070 CB offers hands-free automated pipetting for procedures such as media change, cell seed out and cytotox assays. The system fits into laminar flow hoods from major vendors such as NuAir, Thermo and Baker and, thanks to an innovative light beam monitor, only operates once the hood’s front door is closed. The epMotion 5070 CB can also be used for experiments using hazardous materials inside a fume hood.

According to Holger Eggert, Eppendorf epMotion product manager, ‘The new epMotion 5070 CB enables automation of pipetting for cell culture without the need for complex and expensive robotic systems – meeting the needs of laboratories engaged in cell biology, cancer research, virus research, pharma studies, ADME/Tox and assay development. This is a significant advance which saves time and affords protection from infectious materials or hazardous liquids. In addition, researchers can move from small sample numbers up to 96 or 384-well plates, thereby generating data with greater statistical significance.’

epMotion 5070 CB will be launched by Eppendorf at Analytica: 1–4 April 2008, New Munich Trade Fair Centre, Area B1, Booth 305/404

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ADME-ToxicologyADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Safety EquipmentLaboratory safety equipment is essential to the effective operation of all laboratories and is required to minimize the risk of harm during experiments. Safety equipment includes radiation safety, radioactive / hazardous waste disposal, alarms and personal safety.

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Eppendorf automates cell culture liquid handling within a laminar flow hood