ENPICOM to integrate renowned structural antibody prediction tools developed at the University of Oxford

ENPICOM will expand its IGX Platform to enable new liability analyses for antibody discovery workflows

15 Jun 2021
Tom Casburn
Associate Editor

Product news

ENPICOM, an innovative bioinformatics software engineering company, announced the upcoming expansion of the IGX Platform’s capabilities towards advanced liability prediction. At the Antibody Engineering and Therapeutics virtual conference, the company revealed its plans to integrate the Structural Antibody Prediction Platform (SAbPred) developed by researchers at the University of Oxford.

"SAbPred is a widely recognized and validated tool developed by experts in molecular biology. While our team harbors a lot of knowledge in bioinformatics and software engineering, we believe this powerful combination brings the best of the two worlds. We are elevating our current platform capabilities and deliver an exceptional experience to antibody and vaccine developers looking for a more rapid, efficient, and reliable antibody discovery solution." said Jos Lunenberg, co-founder and Chief Executive Officer at ENPICOM.

"We're very excited to see Oxford Protein Informatics Group’s SabPred tools incorporated into ENPICOM's IGX Platform. This collaboration will open the door for new users to apply our software to the structural analysis of antibodies," said Fergus Boyles, Research Software Engineer at the University of Oxford.

Enabling structural liability analysis at scale

Oxford researchers have developed SAbPred to perform various predictions of antibody properties that can support the discovery process and antibody design. The software helps study antibody properties and generate valuable information for the developability potential of antibody candidates. SAbPred is currently used by leading biopharmaceutical companies to improve the design of antibody-based therapeutics.

By integrating SAbPred tools into the IGX Platform, ENPICOM allows scientists to apply sophisticated algorithms to analyze high-throughput sequencing data inside the scalable and intuitive environment. This integration unlocks new antibody discovery workflows like performing structural analysis of proteins of interest and annotating important liability characteristics to select antibody candidates with good developability properties.

"The integration of SAbBox technology with ENPICOM’s IGX platform is a great case study for impact from research at the Oxford University. We look forward to this launch as it will provide new ways of accessing the SabPred tools on a cloud-based platform," said Sandeep Singh, Senior Licensing and Ventures Manager at Oxford University Innovation.

For more of the latest science news, straight to your inbox, become a member of SelectScience for free today>>

Links

Tags

Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Discovery SoftwareComputational techniques used in both the chemistry and biology aspects of drug discovery, for data acquisition, processing and storage. Software is used for analysis of pathways, target identification, genomics, proteomics, modelling, lead identification, compound analysis and drug modelling among many others. Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.ImmunologyImmunology is the branch of medical science that covers the study of all aspects of the immune system of multicellular organisms.Software SolutionDrug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.