Enabling scalable solutions for biologics and next-generation therapeutic discovery

Catch up on top talks from leading scientists, video interviews, and the latest resources in the field of biologics and therapeutics

8 Feb 2022
Ellie Abbott
Biochemist

Editorial article

Sartorius event image
Register to watch the on-demand presentations here

In this article, we highlight the top talks from our recent virtual event, now available on demand, that you won't want to miss. During the event, hosted in partnership with Sartorius, experts in the field of biologics and therapeutics showcased their research, and leading manufacturers shared their technology solutions with participants from across the globe.

The free-to-attend virtual event showcased hot topics spanning immuno-oncology, neuroscience, infectious diseases, vaccines, vaccine development, advanced cell models, cell line development, and more. The platform featured renowned speakers, interactive booths, resource hubs from leading brands, and opportunities for scientists and manufacturers to connect.

Just a few of the talks now available to watch on demand include:

Design and development of potency assays for an autologous cell therapy for Alzheimer disease

Cell sorting in a busy laboratory

In this expert talk, Prof. Michael Valenzuela, Co-Founder & Chief Scientist at Skin2Neuron, discusses his approach to developing potency assays for an autologous therapy for Alzheimer's disease. He highlights the use of Primaverah® technology, Alzheimer's disease as a therapeutic target, proof of concept animal studies leading to proposed mechanisms of action, and potency assays currently under development.

Watch here

Refining bispecific antibody engineering

Michael  Fiebig

In this presentation, Dr. Michael Fiebig,Chief Scientific Officer at Absolute Antibody, shares his approach to getting started with bispecific antibody engineering. He highlights the core technologies, applications, and designs to consider when engineering bispecific antibodies.

Watch here

Evaluation of checkpoint inhibitor therapies using a mixed lymphocyte reaction (MLR) assay

Kirsty McBain image

Join Kirsty McBain, Associate Scientist iQue® Applications Group at Sartorius, as she gives an overview of advanced high-throughput flow cytometry and highlights case studies of how the iQue® Advanced Flow Cytometry Platform and associated reagent kits can be used to quantify T cell response in MLR.

Watch here

A dissection of SARS-CoV-2 with primary human lung culture systems

Sandra Lawrynowicz image

Sandra Lawrynowicz Leibel, Assistant Professor of Pediatrics, and Ben Croker, Associate Professor, both at the University of California, San Diego, discuss the use of lung organoid models to study the effects of SARS-CoV-2, and cell culture methods for generation of human lung culture systems. They also highlight how to use live-cell imaging to investigate the pathobiology of SARS-CoV-2 infection.

Watch here

Discovery and development of antibody therapies for COVID-19

Zhiqiang Ku image

In this talk, Dr. Zhiqiang Ku, Postdoctoral Fellow at the Brown Foundation Institute of Molecular Medicine, shares how neutralizing antibodies can be used as a drug modality for the treatment of COVID-19, SARS-CoV-2 virology, platforms for antibody discovery, and strategies and technologies for selecting the right antibody combinations.

Watch here

Watch the remaining talks at a time that suits you

Missed one of the presentations? Fortunately, all of the presentations will be available to watch on-demand until March 12 – be sure to register now for access.

Harnessing the power of iPSCs for disease modelling
Dr Sian Humphreys, Scientific Project Manager, Axol Bioscience

Multiplexed functional antibody profiling using advanced flow cytometry
Dr. John O’Rourke, Head of Product Development for Cell Analytics, Sartorius

Live-cell analysis of human neuron-glial cell co-cultures
Dr. Tom Campbell, Senior Scientist, Talisman Therapeutics

Developing an assay platform for screening and characterization of antibody drug conjugates
Rachel Forfar, LifeArc

Enabling next-generation bioanalysis and bioprocessing with Optimer®
Dr. Edward Barnes, Director of Research, Aptamer Group

Advances in 3D cell models for cancer biology using real-time live-cell analysis
Kalpana Barnes, Manager, Cell Imaging Applications, Sartorius

Cell line development: Accelerating process optimization by combining Ambr® 15 cell culture with Octet® titer measurements
Dr. Dirk Müller, Manager of Media & Process Development, Sartorius Lukas Klein, Scientist, Sartorius

From gene cloning to commercialization: Tools for steamlining cell line development
Dr. Stuart Knowling, Senior Scientist, Sartorius

Addressing cancer gene therapy efficacy by real-time live–cell imaging
Dr. Pierre Cordelier, Senior Scientist and Team Leader, INSERM

Efficient detection of airborne viruses: Monitoring air during viral outbreaks
Eric Clement Arakel, Global Project Manager for Sartorius

SelectScience runs 10+ webinars a month across various scientific topics, discover more of our upcoming webinars>>

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.3D Cell CultureCulturing cells in three dimensions allows more physiologically relevant observations to be made regarding cellular interactions and gene expression. 3D models provide a more accurate representation of cells in vivo and are more stable than 2D cultures, making them very useful for long-term studies.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.Cell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.Respiratory InfectionsRespiratory infections are caused by pathogens such as bacteria, viruses, and fungi, leading to diseases like pneumonia, tuberculosis, and COVID-19. It is important to identify respiratory infections quickly in patients to ensure appropriate treatment and care, and to prevent sepsis. Browse our peer-reviewed product directory to find the best tools for respiratory infection detection, compare products, check reviews, and get pricing directly from manufacturers.BioprocessingBioprocessing is the use of biological systems for the conversion of raw materials to desired products. This includes the research, development and manufacturing stages of production and can refer to food processing, small-molecule pharmaceutical manufacture, production of recombinant protein therapeutics, or the generation of renewable energy.3D Imaging3D imaging technologies allow for the visualization and analysis of three-dimensional structures at high resolution. These systems are used in fields like molecular biology, material science, and medical diagnostics. 3D imaging can be applied to visualize cells, tissues, and organs, providing valuable insights into their structure and function. Browse our peer-reviewed product directory to find the best 3D imaging solutions, compare products, check reviews, and get pricing directly from manufacturers.Cancer ResearchCancer research aims to understand the mechanisms of cancer development and progression to improve prevention, diagnosis, and treatment. From molecular biology to clinical trials, research spans a wide range of disciplines, including immunotherapy, targeted therapies, and drug discovery. Explore the best cancer research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.