EKF Diagnostics Highlighting Cancer Molecular Diagnostics Products at ASCO 2015

New PrecisionPath™ NGS panel molecular test for colon cancer to be key focus on Booth #19141

27 May 2015
Lauren Edwards
Editorial

Product news

EKF Diagnostics will be exhibiting its range of molecular diagnostics products supporting personalized medicine in cancer at the 2015 American Society of Clinical Oncology (ASCO) annual meeting, 29th May to 2nd June, McCormick Place, Chicago, Illinois. Here 30,000 oncology professionals from around the world will be brought together to discuss the very latest in treatment modalities, therapies and research in the field, in order to apply this knowledge to enhance cancer patient care. EKF subsidiary, Selah Genomics’ newly introduced PrecisionPath™ next generation sequencing (NGS) technology cancer test will be a key focus on Booth #19141. This first commercially available NGS panel molecular test priced under US$1000, which was recently launched in partnership with Greenville Health systems (GHS), paves the way for accessible, low-cost personalized medicine in colon cancer. At ASCO, key personnel from Selah Genomics will be on hand to discuss how PrecisionPath™ can help oncologists select the most effective treatment options for a patient based on the specific molecular profile of their tumor. Also to be exhibited on the EKF booth, will be EKF Molecular Diagnostics’ PointMan™ DNA enrichment kits for the ultra-low level detection of cancer gene mutations in both tissue and blood biopsies. These include kits for enrichment of cancer biomarkers, such as KRAS, BRAF, EGFR, JAK2 and ESR1. Notably, data has recently been presented which identifies PointMan™ technology as an easy and useful method for non-invasively determining plasma EGFR T790M mutation status in late stage lung cancer patients [1]. Reference:1. Nishikawa, S. et al. Non-invasive analysis for T790M mutations of EGFR using a selective amplification method. American Association for Cancer Research (AACR) Annual Meeting 2015.

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Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Clinical NGSNext Generation Sequencing (NGS) refers to the use of massive parallel sequencing of multiple small fragments of DNA. This high-throughput genomic analysis yields enormous amounts of sequence data, which if appropriately analyzed could have huge potential for clinical laboratories. For this to happen there are technique and bioinformatic hurdles to be overcome.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.Precision MedicinePrecision medicine refers to the idea of customized healthcare, where medical decisions and treatments are tailored to the individual patient. Molecular diagnostics, companion diagnostics and Next Generation Sequencing (NGS) play a pivotal role in this approach.
EKF Diagnostics Highlighting Cancer Molecular Diagnostics Products at ASCO 2015