Ebola Outbreak in the Democratic Republic of Congo (DRC)

Wellcome trust to support rapid response in the DRC

17 May 2018
Frankie MacDonald
Administrator / Office Personnel

Industry news

Dr Jeremy Farrar, Director of Wellcome said: “Confirmation of an Ebola case in Mbandaka, a major urban centre, around 150km from the cases reported last week, is an extremely concerning development. Ebola spreads rapidly, and this outbreak is in an area where people connect, trade and travel - an environment ripe for spreading disease. Swift and decisive action by the DRC and WHO to bring this outbreak under control means vaccines are now in the affected area".

In December 2016, final trials of an Ebola vaccine, with funders including Wellcome, UK and the Norwegian governments, confirmed it provides a high level of protection against a strain of the deadly disease. This vaccine, made by Merck, Sharpe & Dohme, was one of a number developed rapidly during the 2014-16 epidemic but came too late to have a significant impact. Several other vaccines are also in development, including candidates from Johnson & Johnson, GSK, Russia and China

“Had a vaccine been available earlier alongside other critical public health interventions in the devastating epidemic of 2014 to 2016, thousands of lives might have been saved. Thanks to rapid national response and global collaboration, this time around we are in a better position to protect the communities at risk and the health workers dedicated to protecting lives. But this will be an incredibly challenging operation, across a vast area and fragile health systems – and cannot be limited to deployment of vaccines.

“Wellcome has made an initial fund of up to £2 million available to support the rapid response underway. Further funding will be needed, and we are working with our global partners, through the Global Research Collaboration for Infectious Disease Preparedness (GLOPID-R) network and the WHO to address this.”

Links

Tags

Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.EbolaThe Ebola virus outbreak in West Africa is the largest in history. Rapid diagnostic tests for this hemorrhagic fever are desperately needed, and companies are working hard to develop new point-of-care, RT-PCR and automated desktop Ebola kits and systems.Vaccine DevelopmentVaccine development focuses on creating immunizations to protect against infectious diseases. The process involves identifying antigens, developing and testing vaccine efficacy, and ensuring safety through preclinical testing and multiple clinical trial phases. Scientists use various approaches, including weakened or inactivated viruses, protein subunits, or mRNA. Advanced platforms and rapid diagnostic tools aid in vaccine research and testing. Explore vaccine development solutions in our peer-reviewed product directory; compare products, read reviews, and get pricing directly from manufacturers. VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.