Easy & Affordable Flow Cytometry and Cell Counting

15 Dec 2006

Product news

Guava Technologies, Inc. has announced a new 8-page brochure introducing and discussing how its range of easy-to-use and affordable cell analysis systems have streamlined and simplified fluorescent cell and bead-based assays by integrating instrument, software and reagents into a turnkey solution.

A pdf copy of the new brochure 'The Power of easy and affordable Flow Cytometry & Cell Counting' can be obtained from the online library, product information section found on the article webpage or by clicking 'request info'.

The widespread desire to gain a 'systems perspective' by analysing whole cells has fuelled a rising interest in cell- and bead-based assays for basic research, drug discovery, process development and clinical research. Studying intact individual cells provides intimate knowledge of how various biological pathways can interact. In addition, cellular studies can cost-effectively expedite target validation, lead optimisation, process development, toxicity determinations, and clinical trials.

The brochure describes Guava's patented microcapillary, laser-based technology for detecting mammalian and microbial cells and beads. The benefits of the technology including ease-of-use, data quality, productivity, compact footprint, very small sample size, reduced reagent usage, minimal waste and affordability are illustrated compared to traditional techniques for cell counting and analysis. An introduction is provided to each of the comprehensive and growing portfolio of optimised reagent assays for cell counting & viability, cell cycle, multicolour antigen detection, apoptosis, mitochondrial membrane potential, fluorescent proteins, cell tracking, cell proliferation, cytotoxicity, cell painting and hybridoma screening.

Guava Technologies, Inc., a privately held biotechnology company, is the leading provider of on-demand, easy-to-use single cell analysis systems. Guava Personal Cell Analysis (PCA™) systems, including the Guava PCA, Guava PCA-96, Guava EasyCyte™, Guava EasyCyte Plus and EasyCyte Mini systems, are integrated, fully optimised, benchtop microcapillary cytometry systems with embedded absolute cell counting capability. Used worldwide by the life sciences, biotechnology, and pharmaceutical industries, as well as clinical testing institutions (outside the United States and Europe), Guava's products have broad applications in scientific research and throughout the drug discovery and lead optimisation process, as well as for cell counting and optimisation of commercial biopharmaceutical production. Guava offers a variety of assays and dedicated software modules for the Guava PCA systems, enhancing the system's overall ease-of-use.

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ADME-ToxicologyADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.