SelectScience
Join Free
Accelerating Science
NewsDrug discovery > Target Discovery

Drug Discovery & Development Scientists’ Choice Awards winners announced at SLAS2023

SelectScience

Agilent Technologies, Sartorius, and Corning Life Sciences among those recognized

28 Feb 2023
Blake Forman
Content Creator

Editorial article

The Seahorse XF Pro Analyzer with the 2023 Scientists' Choice Awards winner badge
The Seahorse XF Pro Analyzer from Agilent Technologies was voted Best New Drug Discovery & Development Product of 2022

The world’s most innovative and effective technologies advancing drug discovery and development have been recognized during a special ceremony at the 2023 SLAS International Conference and Exhibition. Winners of the 2023 Scientists’ Choice Awards® were announced by SelectScience® Vice President, Jay Leech, and Executive Editor, Dr. Lois Manton-O'Byrne.

Now in their 16th year, the awards are unique in the industry as they are chosen by scientists. Each year, we invite scientists from around the globe to participate by nominating, reviewing, and voting for the lab products that have had the greatest impact on their work. Read on to reveal your chosen winners.

Best New Drug Discovery & Development Product of 2022

The award for Best New Drug Discovery & Development Product of 2022 goes to the Seahorse XF Pro Analyzer by Agilent Technologies, as voted for by scientists around the world.

Agilent Seahorse XF Pro Analyzers measure the oxygen consumption (OCR) and extracellular acidification rate (ECAR/PER) of live cells in a 96-well format. OCR and ECAR or PER are key indicators of mitochondrial respiration and glycolysis as well as ATP production rate. Together, these measurements provide a systems-level view of cellular metabolic function in cultured cells and ex vivo samples.

Your runners-up are:

Steve Rees OBE, Vice President Discovery Biology, AstraZeneca, joined the Scientists' Choice Awards celebration as a special guest to speak about communication in science

Drug Discovery & Development Webinar of the Year

This year’s Webinar of the Year is awarded to Dr. Archana Thakur, Associate Professor of Medicine, Director of Human Cellular Therapeutics cGMP Core, University of Virginia, School of Medicine, in associate with Agilent Technologies. The webinar, titled ‘Bispecific-antibody-armed, metabolically enhanced headless CAR T cells: Safe and effective serial killers of solid tumors’, available to watch on demand, discusses metabolically enhanced headless CAR T (hCAR T) cells armed with bispecific antibodies (bsAbs) that were created as safe, effective serial killers of tumor targets.

Drug Discovery & Development Editorial Article of the Year

This winning article is titled ‘Identifying tumor-specific cancer treatments using patient-derived tumor organoids’ and features technology from Corning Life Sciences.

In this interview, Dr. Benjamin Hopkins, Assistant Professor at the Icahn School of Medicine at Mount Sinai, New York, discusses how his team is pairing comprehensive genomics with drug screening of high-fidelity patient-derived organoids to help identify effective therapeutic strategies for cancer patients.

Drug Discovery & Development Video of the Year

This year’s winning video is awarded to a presentation titled ‘Single cell antibody discovery using 'Islands of automation', this video discusses work to automate single-cell processes used for biologics discovery specifically antibody discovery.

From top to bottom: Michelle Kleist, Marketing Manager, and Kellie Chadwick, Agilent Technologies, Chris Ward, Marketing Communications for Cell Therapy & Bioprocess, Corning Life Sciences, Andrea Brütsch, Global Product Manager, METTLER-TOLEDO, and Hannah Puzas, Sartorius Group.

Drug Discovery & Development Application eBook of the Year

The Drug Discovery & Development Application eBook of the Year Award goes to Sartorius Group for ‘Achieve lab weighing compliance with ease’. This application compendium illustrates the importance of weighing compliance in the regulated lab and provides you with the tools to achieve greater lab efficiency.

Drug Discovery & Development Email of the Year

The winner in the Email of the Year category goes to ‘Be compliant with European Pharmacopoeia General Chapter 2.1.7’, from Mettler-Toledo GmbH. The winning email featured a downloadable white paper explaining the scope and requirements of Ph. Eur. Chapter 2.1.7 and what you need to do to ensure compliance.

Do you use any of these lab products? Share your opinion today by leaving a lab product review>>


Visit the Scientists’ Choice Awards website for more information

Links

SelectScienceCompany website

Tags

Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Animal ModelsThe use of non-human animals in experiments or behavorial observations. The research is conducted inside universities, medical schools, pharmaceutical companies, farms, defence establishments, and commercial facilities that provide animal-testing services to industry. It includes pure research such as genetics, developmental biology, behavioral studies, as well as applied research such as pharmaceutical testing in pre-clinical, before human, studies. Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.OsmometryIn osmometry, the osmotic strength of a solution, colloid or compound is measured. Osmotic strength is a measurement of the total concentration (distinct from molarity) of dissolved material in solution. This technique is often used for the determination of average molecular weight.SLASThe Society for Laboratory Automation and Screening (SLAS) is an organization focused on laboratory automation, high-throughput screening, and biotechnology innovation. SLAS promotes scientific advancements through conferences, publications, and industry collaborations.

Related articles