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Dotmatics Launches New Bioinformatics Software to Aid Analysis of Whole Genome and Protein Data

Dotmatics Limited
17 Nov 2016
Lois Manton-O'Byrne, PhD
Executive Editor

Product news

Dotmatics, a leading provider of scientific informatics solutions and services, today announced Vortex for Bioinformatics, an easy-to-use program designed to allow all bioscientists to analyze and visualize their data to make better-informed decisions.

Built into the long established and widely used Vortex program, Vortex for Bioinformatics can handle whole genome, antibody, protein and peptide data types and can scale to handle massive amounts of data including whole genomes on a laptop. With novel methods to relate biologic structure and sequence to activity, Vortex for Bioinformatics helps users understand assay results and drive forward the design of biologics with high performance analysis and visualization.

“Traditionally, a small number of experts are required to perform the analysis and visualization of bioinformatics data,” said Mike Hartshorn, PhD, Dotmatics Chief Science Officer. “These are the individuals who can script together the algorithms and programs needed to complete the discovery of knowledge. With Vortex for Bioinformatics, Dotmatics is broadening access to critical scientific methods while enabling discovery at the bench.”

Once a user loads bioinformatics data from files or directly from databases, Vortex for Bioinformatics displays the live sequences in a variety of formats. A selection of analysis algorithms is available including alignment, cross-alignment, clustering and search. The software makes intelligent selections of the correct methods to use based on the number and type of the sequences being analysed. This ensures that users can obtain appropriate results without having to know all of the algorithmic details, while power users can make manual selections. Expert bioinformatics can integrate additional methods via scripting

When used in conjunction with Dotmatics 5.0 informatics applications such as BioELN and BioReg, Vortex can seamlessly become an integral part of the biologics discovery workflow.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Data AnalysisThe analysis of data is the process of transforming, modeling and evaluating data to discover useful information from experimental results. Peptide MappingProtein StructureProtein structure refers to the three-dimensional arrangement of amino acids in proteins, determining their function. Understanding protein structure is key in drug discovery, enzymology, and molecular biology. Explore protein structure analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Genome SequencingGenome sequencing involves determining the complete DNA sequence of an organism's genome. It provides crucial information about genetic variations, mutations, and diseases. Advances in sequencing technologies, such as next-generation sequencing (NGS), have accelerated research in genomics, diagnostics, and personalized medicine. Explore genome sequencing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.

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