Dolomite’s Resealable Chip Interface Offers Easy Access to Microfluidic Chip Surface

11 Nov 2014

Product news

Dolomite – the pioneering microfluidics specialist – has launched a Pressure-driven Resealable Chip Interface System designed for applications requiring quick and easy access to the microfluidic chip surface. Compact and robust, this easy-to-use system enables tool-free assembly of glass, quartz or polymer resealable chips, allowing the user to deposit reagents, sensors, biosensors or cells onto the chip base layer for exposure to the fluid stream.

The modular, flexible system comprises a Resealable Chip Interface – allowing up to eight fluidic and eight electrical connections per chip – 4-way linear connectors, and Mitos Pressure Pumps for pulseless, stable flow from 70 nl to 5 ml a minute, at pressures of up to 10 bar. For direct, accurate control of flow rates, Mitos Flow Rate Sensors can also be included. The versatile Resealable Chip Interface System is ideal for a broad range of applications, including biosensor testing, cell culture analysis, dielectrophoresis experiments, impedance detection and applications where cleaning or replacement of some parts of the system is required between experiments. The system is also compatible with a range of microscope systems – for straightforward imaging and recording – and Dolomite’s optional Mitos PPump Remote Chambers, which allow up to 30 ml of fluid to be conveniently located in a pressurized, sterile environment for easy temperature control or agitation, ensuring you can develop a set-up to meet your application needs.

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ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MicrofluidicsMicrofluidics is the science of manipulating small volumes of fluids in micro-sized channels. It is widely used in diagnostics, drug development, and lab-on-a-chip technologies. Microfluidic devices can enable rapid, cost-effective, and high-throughput analysis of biological samples. Browse our peer-reviewed product directory to find the best microfluidic devices, compare products, check reviews, and get pricing directly from manufacturers.
Dolomite’s Resealable Chip Interface Offers Easy Access to Microfluidic Chip Surface