Dolomite Microfluidics offers new microfluidic chips for Telos system

22 Oct 2019
Arran Tabary-Davies
Microbiologist

Product news

Dolomite Microfluidics has launched a number of new microfluidic chip options for its innovative Telos system. The expanded range of high-quality glass chips is intended to open up a number of new applications for the high-throughput Telos platform, providing a genuinely scalable option for droplet, particle and flow product generation across a wide range of industries.

The expanded range now includes a 50 μm version of the Telos 2 Reagent Chip to complement the original 100 μm option, allowing the formation of monodisperse, 10 to 75 μm droplets containing two reagents. The growing popularity of microfluidic cell and particle encapsulation techniques has also led to the development of the Telos 2 Reagent Encapsulation Chip. Available in 30 and 50 μm sizes, these chips lack the on-chip filters built into the standard reagent chips, allowing the straightforward encapsulation of cells, beads or particles in 5 to 75 μm droplets. Finally, the Telos 1 Reagent 3D Flow Focusing chips have been created for single reagent applications that suffer from high surface fouling using standard chip geometries. Each fluid junction has a redesigned ‘pore’ structure on the outlet side, promoting earlier detachment of the droplets from the walls of the channel to reduce fouling and allow longer production runs.

All Telos chips have seven parallel junctions, and are available with hydrophilic, hydrophobic and fluorophilic coatings to allow the generation of oil-in-water, water-in-oil and water in fluorinated oil emulsions. Up to 10 chips can be run in parallel on the Telos system – with integrated valves for rapid start-up and individual chip control – providing 70 junctions for flexible processing over a wide range of pressures and temperatures. This innovative system removes the low throughput limitation of individual microfluidic chips, enabling up to 1 tonne of droplets or particles to be produced in a month.

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Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.MicrofluidicsMicrofluidics is the science of manipulating small volumes of fluids in micro-sized channels. It is widely used in diagnostics, drug development, and lab-on-a-chip technologies. Microfluidic devices can enable rapid, cost-effective, and high-throughput analysis of biological samples. Browse our peer-reviewed product directory to find the best microfluidic devices, compare products, check reviews, and get pricing directly from manufacturers.
Dolomite Microfluidics offers new microfluidic chips for Telos system