SelectScience
Join Free
Accelerating Science
NewsLife Sciences

DNASTAR Awarded Clinical Research Software Phase II SBIR Grant

DNASTAR Inc.
21 Jul 2013
Emily Marquez-Vega
Publishing / Media

Product news

DNASTAR® announced that it received a Phase II SBIR grant award from the National Institutes of Health entitled, “Association Analysis Software for Mining Clinical Next-Gen Sequencing Data”. This is the second phase of a project initially funded in 2012 to support the company’s research and development aimed at expanding its industry-leading sequence assembly and analysis software from broad research usage to the clinical research market.

Tom Schwei, Vice President and General Manager of DNASTAR, commented, “There is a growing trend to consider analyzing genomic information as part of clinical studies, whether retrospectively or prospectively. Increasingly, clinical researchers are seeing that including a genomic component to clinical research can uncover key information that is critical in moving a study forward. We are pleased to receive this funding to continue our work in adapting our general research software to the specific needs of clinical researchers. As part of this grant research program, we will be collaborating with clinicians on several cancer studies to ensure our software fully meets their needs.”

Schwei concluded, “This project ties in well with DNASTAR’s long-term strategy, which is to build on our strength in sequencing software for the general research market and expand into a wide range of related fields. Clinical research is one of those very important areas we are addressing for the future.”

Links

DNASTAR Inc.Company website

Tags

Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.NGS SoftwareClinical NGSNext Generation Sequencing (NGS) refers to the use of massive parallel sequencing of multiple small fragments of DNA. This high-throughput genomic analysis yields enormous amounts of sequence data, which if appropriately analyzed could have huge potential for clinical laboratories. For this to happen there are technique and bioinformatic hurdles to be overcome.

Related articles

DNASTAR Awarded Clinical Research Software Phase II SBIR Grant