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Discovery of a druggable pocket in SARS-CoV-2 Spike: New avenue to defeat COVID-19?

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Join us on Tuesday, July 28, to learn about the structural link between COVID-19 pathology and the virus itself and how this may lead to novel therapeutics

12 Jul 2020
Edward Carter
Publishing / Media

Expert insights

Imre Berger, Founder and Managing Director at the Max Planck-Bristol Centre for Minimal Biology

COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Key to SARS-CoV-2 therapeutic development is to unravel the mechanisms driving high infectivity, broad tissue tropism and severe pathology. SARS-CoV-2 is decorated by multiple copies of a glycoprotein, called Spike, which is key to such severe infectivity.

Using cryo-electron microscopy and cloud computing, Genscript has discovered a potentially druggable pocket within the SARS-CoV-2 Spike, which appears to be present in the highly pathogenic coronaviruses that caused previous SARS and MERS outbreaks

Watch this webinar, presented by Imre Berger, Founder and Managing Director at the Max Planck-Bristol Centre for Minimal Biology, to find out for the first time the structural link between COVID-19 pathology and the virus itself, setting the stage for developing new therapeutic interventions to combat and defeat COVID-19.

Register here

Key learning objectives:

Learn about the high-tech science technologies and techniques being used to defeat the global COVID-19 epidemic.

Who should attend?

  • COVID-19 researchers
  • R&D scientists in academia and industry
  • Biologists
  • Biochemists
  • Those working within CROs and CDMOs
  • Drug developers

Certificate of attendance

All webinar participants can request a certificate of attendance, and a learning outcomes summary document for continuing education purposes.

This webinar will run on Tuesday, July 28, at:

  • 14:00 BST
  • 15:00 CEST
  • 09:00 EDT
  • 06:00 PDT

Register for this webinar here>>

SelectScience runs 3-4 webinars a month across various scientific topics, discover more of our upcoming webinars>>

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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Electron MicroscopyElectron microscopes (EM) are used to create high-resolution images of samples at the nanoscale by means of an accelerated beam of electrons as a source of illumination. Types of electron microscope include scanning electron microscopes (SEM), transmission electron microscopes (TEM), scanning transmission electron microscopes (STEM) and cryo-electron microscopes. Focused ion beam (FIB) microscopes are useful for modifying or milling a sample surface with nanometer precision, as well as imaging. Find the best electron microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Structural BiologyDrug DevelopmentDrug development refers to the process of bringing a new drug to market.CoronavirusCoronaviruses are a large family of viruses that can cause illnesses ranging from the common cold to more severe diseases like COVID-19. Research into the biology, transmission, and treatment of coronaviruses has become a global priority, particularly since the emergence of SARS-CoV-2. Understanding the virus�s structure and behavior is essential for developing vaccines, diagnostics, and antiviral treatments. Explore our peer-reviewed product directory to discover the latest research tools, diagnostic tests, vaccines, and treatments for coronavirus, compare products, read reviews, and receive pricing directly from manufacturers.

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