DiscoveRx at SLAS2014: Integrating Target Biology & Phenotypic Screening

20 Jan 2014
Sarah Thomas
Associate Editor

Product news

DiscoveRx offers both phenotypic and target-based drug discovery solutions! With the largest portfolio of target-based assay solutions PLUS the world’s largest collection of human primary cell systems for phenotypic drug discovery, DiscoveRx is Integrating Target Biology with Phenotypic Screening.

Visit DiscoverRx at Booth #1035 to learn how our integrated biological approach can accelerate your drug discovery programs!


• >45 BioMAP® human primary cell profiling systems
• 1000's of target-based assay solutions
• Meet with our drug discovery experts to discuss your screening challenges
• InCELL Hunter™ technology platform for measurement of target engagement in live cells
• Plus, enter to win a free assay-ready kit of your choice!
Visit the DiscoveRx SLAS2014 webpage by clicking on the company website link below for complete details.


Conference Event & Activity Schedule

Podium Presentation
Tuesday January 21, 10:30 am - 11:00 am
Predictive Models for Mechanism of Action Classification from Phenotypic Assay Data: Application to Phenotypic Drug Discovery
Speaker: Ellen L. Berg (BioMAP®/DiscoveRx)
Track: Informatics
Session: Title Extracting Meaning from Complex Data

Tutorial
Tuesday January 21, 2:00 pm - 2:45 pm Room 28C
InCELL Hunter™: A Novel Target Engagement Platform Enabling Direct Measurement of Compound Binding to Intracellular Targets in Intact Mammalian Cells
Speakers: Doug Auld, PhD (Novartis) & Jan Lamerdin, PhD (DiscoveRx)

DiscoveRx Scientific Posters
Monday, January 20, 1:00 pm – 3:00 pm
Detection of Cytokine and Growth Factor Receptor Dimerization using Enzyme Fragment Complementation (230)
Track Title Assay Development and Screening

Monday, January 20, 2014, 1:00 pm – 3:00 pm
Primary Human Cell Systems for Drug Discovery (180)
Track Title Assay Development and Screening

Tuesday, January 21, 2014, 1:00 pm – 3:00 pm
Detection of Endogenous Ligand Bias: A Case Study Using the Chemokine Receptor Family (261)
Track Title Assay Development and Screening

Tuesday, January 21, 2014, 1:00 pm – 3:00 pm
Dual Kinase/Bromodomain Inhibitors for Rationally Designed Polypharmacology (219)
Track Title Assay Development and Screening

Links

Tags

High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.SLASThe Society for Laboratory Automation and Screening (SLAS) is an organization focused on laboratory automation, high-throughput screening, and biotechnology innovation. SLAS promotes scientific advancements through conferences, publications, and industry collaborations. Metabolic Phenotyping
DiscoveRx at SLAS2014: Integrating Target Biology & Phenotypic Screening