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Discover the genetic dependencies of antibiotic function

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Join us on Friday, June 19, to find out how massively parallel microbial strain engineering may lead to the development of novel therapeutics to combat the most difficult antibiotic-resistant pathogens

8 Jun 2020
Edward Carter
Publishing / Media

Expert insights

Dr. Dan Held, Director of Synthetic Biology, Microbial Applications Developmnent at Inscripta

Massively parallel microbial strain engineering on a CRISPR-based benchtop platform has enabled the exploration of the genetic dependencies of antibiotic function in unprecedented scale and detail. The ability to design and deliver precisely determined edits throughout the entire E. coli genome has resulted in an unparalleled opportunity to query a diverse population of strain variants for their growth responses to antibiotics from multiple different functional classes.

Find out more in this expert webinar as Dr. Dan Held, Director of Synthetic Biology, Microbial Applications Development, Inscripta, outlines how the knowledge garnered through the use of this strain engineering technology has significant potential to lead to the development of novel therapeutics against our most difficult antibiotic-resistant pathogens.

Register here

Key learning objectives

  • Introduction to Inscripta’s Onyx™ microbial benchtop digital genome editing platform
  • Example application of genome-wide strain engineering in E. coli
  • Opportunity to explore a deep and comprehensive data set revealing the genetic responses to exposure to different antibiotics

Who should attend?

  • Professional groups: Lab management (director, PI, group leader, dept. chair), core facility manager, professor/instructor, research scientist/staff scientist, postdocs
  • Research areas: Drug target identification, functional genomics, antimicrobial discovery and disease research, industrial bioproduction
  • Technologies of interest: CRISPR, microbial gene editing, genome engineering, synthetic biology, forward engineering of microorganisms
  • Demographic: Scientists located in the USA, Canada, countries part of the EU, and the UK, due to scheduled product availability

This webinar will run on Friday, June 19, 2020, at:

  • 16:00 BST
  • 17:00 CEST
  • 08:00 PDT
  • 11:00 EDT

Register to watch the full webinar here>>

This webinar is part of the SelectScience Advances in Microbiology Webinar Series >>

SelectScience runs 3-4 webinars a month across various scientific topics, discover more of our upcoming webinars>>

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Tags

Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Genetic EngineeringAntibiotic ResistanceAntibiotic resistance poses a significant threat to public health driving innovation and change through antibiotic stewardship efforts. Ongoing research and diagnostic efforts focus on new treatments and detection methods. Explore antibiotic resistance research and diagnostic tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.CRISPRCRISPR technology enables precise editing of genes, allowing scientists to modify DNA at specific locations. This revolutionary tool is used in genetic research, drug development, and gene therapy. CRISPR has applications in agriculture, disease treatment, and creating genetically modified organisms (GMOs). Explore CRISPR solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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Discover the genetic dependencies of antibiotic function