Discover a New Level of Simplicity with Olympus’ CellSens 1.11 Imaging Software

26 May 2014
Sarah Thomas
Associate Editor

Product news

With Olympus’ unique GEM interface integrated into the latest release of the cellSens imaging software, executing even the most intricate life science imaging experiments is now realized with outstanding ease and efficiency.

Personalized automation is the key to managing complex multi-dimensional experiments, and the latest Olympus cellSens imaging software (version 1.11) seamlessly controls motorized hardware to allow effortless set-up of complex acquisition sequences and protocols. The unique Graphical Experiment Manager (GEM) interface allows the user to "draw" their experimental schematic on-screen with familiar “drag and drop” actions, enabling complete control and experimental set-up of motorized components and accessories with almost no need for training. The capabilities of this intuitive interface are now expanded to the control of motorized stages, enabling the easy automation of multi-position experiments such as individual scanning protocols performed at different positions on a multiwell plate.

Providing insights into a host of biological processes, additional new features of the software include online ratiometric analysis, delivering results in real time and control of rapid focusing devices for fast 3D applications, while also supporting the latest cameras and image-splitter components. From image acquisition to analysis, expanding the range of components compatible with cellSens presents new avenues of exploration within life science. Additional models of EMCCD and sCMOS cameras are now supported such as the Hamamatsu ImagEM X2 and the Andor Zyla 4.2, delivering rapid and sensitive imaging; while 3D applications benefit from the integrated control of piezo-driven devices, for ultra-fast Z-stacking and focusing. Multi-channel imaging of samples with fast dynamics is now supported through the use of an image splitter, with up to four emission channels acquired at the same precise moment. The exact synchronization of multiple wavelengths also quickly produces reliable images for advanced applications such as FRET and ratiometric analysis. Moreover, ratiometric analysis can now be achieved “online”, enabling the real-time tracking and updating of ratiometric images and graphs during experiments.

These combined features make cellSens version 1.11 ideal for a range of life science imaging applications, enabling any user to rapidly and easily generate reliable results.

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Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.sCMOSCell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.Live Cell ImagingLive cell imaging is the study of living cells using microscopes and high-content imaging systems. This technique provides in-depth insight into fast and complex biological processes, by allowing dynamic imaging of living cells instead of acquiring an individual image at a single point in time.
Discover a New Level of Simplicity with Olympus’ CellSens 1.11 Imaging Software