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Direct Ionization System on Display at analytica

Protea Biosciences Group, Inc
9 Apr 2012
Roger Wayman
Administrator / Office Personnel

Product news

Protea Biosciences Group, Inc. will be presenting the LAESI DP-1000 system at analytica this year. Visit Hall A3, Booth 541 to see how the LAESI DP-1000 is revolutionizing mass spectrometry imaging and high-throughput workflows.

The LAESI DP-1000 Direct Ionization System uses the natural properties of biological samples to enable the identification, characterization, profiling, and quantitation of biomolecules by mass spectrometry with no or minimal sample preparation. Performing extraction/ ionization at ambient pressure, LAESI DP-1000 allows mass spectrometry investigation to all vacuum-incompatible samples. Used in both 2D and 3D imaging investigations as well as with open-well plate analysis, the LAESI DP-1000 offers new opportunities in bio-analytics, eliminating complicated and time consuming sample preparation steps while simultaneously giving scientists direct access to biomolecules from tissues, living cells and colonies. Used in the fields of biomarker discovery, pharmacokinetics studies and in-vivo/ vitro toxicological screening, LAESI DP-1000 provides unparalleled information that facilitates drug discovery and development.

The LAESI DP-1000 changes the way scientists approach biomolecule analysis. Using this technology, it is possible to directly look into what is happening inside a biological system, examining the molecules where they are and as they are in nature. LAESI DP-1000 facilitates biologists to better understand the biodynamics of cell cultures and living colonies and provides biochemists the opportunity to analyze distribution profiles of metabolites in a tissue. The process itself offers unparalleled speed to the mass spec workflows, allowing scientists to truly see beyond experimental expectations.

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Toxicology / Drugs of Abuse TestingToxicology and Drugs of Abuse Testing is the investigation into toxic and illegal substances found at the scene of a crime or from a suspect and / or victim associated with a scene of a crime. Analyzers, immunoassays and drugs of abuse test kits and presumptive test kits are an essential aspect of toxicology investigation.Cell Biodynamics3D Imaging3D imaging technologies allow for the visualization and analysis of three-dimensional structures at high resolution. These systems are used in fields like molecular biology, material science, and medical diagnostics. 3D imaging can be applied to visualize cells, tissues, and organs, providing valuable insights into their structure and function. Browse our peer-reviewed product directory to find the best 3D imaging solutions, compare products, check reviews, and get pricing directly from manufacturers.Pharmacokinetics

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