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DiaSorin Displays Latest Infectious Disease Assays at Biomedica 2012

Diasorin Ltd
26 Apr 2012
Sonia Nicholas
Managing Editor and Clinical Lead

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DiaSorin was displaying its latest 3 infectious disease assays at BioMedica in Dublin 2012 this week. The HIV Ab/Ag, HBsAg and HCV Ab assays are all chemiluminescence assays for use on the new DiaSorin LIAISON® XL platform.

The LIAISON® XL murex HIV Ab/Ag sandwich chemiluminescent assay automatically combines results from anti-HIV antibody and HIV p24 antigen assays giving the test superior sensitivity for early diagnosis. The test can detect all major HIV variants and subtypes with a high level of reproducibility.

The LIAISON® XL murex HCV Ab indirect chemiluminescent assay uses high-quality recombinant antigens to detect all major HCV genotypes. HCV is diagnosed serologically by detecting antibodies specific to the hepatitis C virus (anti-HCV).

The LIAISON® XL murex HBsAg Quant is a direct two-step sandwich chemiluminescence assay based on novel murine monoclonal antibodies (Mabs). Patented technology means that the test has the unique capability to detect both HBsAg mutants and the HBsAg genotypes. Mabs are capable of binding the unfolded antigen in the presence of a high concentration of detergents and are directed towards the “classical a” loop region as well as to highly conserved domains derived from both the internal hydrophilic loop and the transmembrane regions. The technology is highly reproducible and shows excellent sensitivity and specificity.

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ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.HepatitisHIV and AIDSBlood tests are the most common way to identify and monitor HIV and AIDS. Current methods include ELISA, Western blot, RT-PCR viral load and CD4/8 testing. Areas for development include point-of-care assays for use in developing countries, and self-testing ‘at home’ HIV kits.

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DiaSorin Displays Latest Infectious Disease Assays at Biomedica 2012