Deerac Fluidics, Labcyte, Promega, BMG Labtech and Corning Sponsor Workshop at SBS Meeting in St. Louis

17 Mar 2008

Product news

Deerac Fluidics, Labcyte, Promega, BMG Labtech and Corning are sponsors of a special workshop that will take place prior to the start of SBS. The workshop will be held on Sunday, April 6th from 9:30am - 12:30pm at the America’s Center St. Louis, room 231. The Workshop title is ‘Assay Optimization and Kinase Profiling in uHTS Format’. Breakfast will be served at this event.

Successful kinase screening requires precise liquid handling, robust assays, reliable plates, and sensitive detection methods. With the increasing number of options available to the screener, it is a challenge to choose which are best suited for a particular application. This workshop demonstrates the complementarity of diverse technologies for a 1536-well kinase assay application.

Using a luminescent kinase technology platform from Promega, we demonstrate the optimization of kinase assays with the Deerac Fluidics Equator dispenser, using assay plates from Corning and with luminescent detection by BMG LABTECH's Pherastar. Following assay optimization, the Labcyte Echo® 555 liquid handler is used for ultra low-volume compound dispensing for screening and compound titration applications. Data show that miniaturization does not compromise quality when lower volume assays are required.

To register for the workshop please go to the article webpage.

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Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.
Deerac Fluidics, Labcyte, Promega, BMG Labtech and Corning Sponsor Workshop at SBS Meeting in St. Louis