DASGIP Launches Micro-bioreactor for High Throughput Screening

30 Oct 2007

Product news

DASGIP AG, a leading manufacturer of parallel bioreactor systems, announced the launch of a miniature bioreactor system for high throughput screening at Biotechnica, 9 – 11 October 2007, in Hanover, Germany. The "DASGIP BioLector" has been developed by m2p-labs, Aachen, Germany, who entered into a partnership with DASGIP to bring the new product to market. Under the agreement, DASGIP has marketing rights in North-America and in Europe.

The DASGIP BioLector monitors cell growth and protein production in up to 96 wells online and in parallel. Additionally, pH or dissolved oxygen can be monitored in each well. Continuous shaking allows uninterrupted aeration by gas exchange between the cells and their environment. The BioLector provides an ideal gas atmosphere for different cell types.

With DASGIP BioLector, operators are able to screen multiple cell lines or strains for growth and expression levels in parallel. Working volumes of the 48- and 96-well plates range from 100μL to 1000 μL per well. Once the candidates of interest are selected, a tailored process can be developed and optimized in DASGIP Parallel Bioreactor Systems, which provide working volume from 35mL to 15L in up to 16 bioreactors in parallel. Therefore, the new parallel screening tool not only makes product development more efficient, but also rounds up DASGIP’s existing fermentation and cultivation solutions perfectly.

”Customers using the DASGIP systems will benefit extraordinarily in process development. With the
new BioLector they benefit from higher efficiency in earlier phases of their value chain”, Dr. Matthias Arnold, CSO DASGIP. The figure above shows how DASGIP products improve and streamline research and process development.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.