CYTOO Launches 2D+ Solutions at HCA

2 Jan 2013

Product news

CYTOO, a life science systems & tools company providing disruptive solutions for cell-based assays and High Content Screening (HCS), will launch the 2D+ Solutions at the High Content Analysis (HCA) Annual Meeting in San Francisco. CYTOO’s 2D+ Solutions open fresh perspectives for cell based assay development in drug discovery.

CYTOO’s 2D+ Cell Culture Platform is based on standard and custom adhesive micropatterns in 96-well plates to guide cell architecture and behavior in culture. By defining the 2D topology of cell adhesion, the 2D+ Cell Culture Platform enables fine control of the spreading and 3D shape of cultured cells in single- or multi-cellular configurations. This approach results in control of cell contractility, cell polarity, organelle positioning, and cell division axis. This technology addresses a major concern with traditional 2D culture, in which cells spread and move in an uncontrolled manner, introducing a considerable but unnoticed variability in cell function.

CYTOO’s Custom Solutions bring expertise, resources and technology to address current bottlenecks in cell based assay development and screening. 2D+ Custom Solutions begin with an in-depth analysis of the customer’s assay, by experienced PhD-level experts of the 2D+ technology.

The 2D+ Custom Solutions process includes: Exploratory solutions to guide customers through the initial exploration of the 2D+ technology; Assay development to select the best ecosystem for the requested cells; Screening to run small and medium screens.

Attendees are invited to visit HCA booth #24 to discuss their application with Pauline Poydenot, Head of Cell Assay Services, and Myles Fennell, Application Development Leader.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell GrowthCell growth refers to the process by which cells increase in size and number. It is essential for tissue development, wound healing, and cancer research. Understanding and controlling cell growth is a fundamental part of cell biology and regenerative medicine. Browse our peer-reviewed product directory to find the best tools for studying cell growth, compare products, check reviews, and get pricing directly from manufacturers.