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CyBio and MACHEREY-NAGEL collaborate to develop applications for automated DNA/RNA preparation

Analytik Jena GmbH+Co. KG
30 Jul 2007

Product news

CyBio AG, manufacturer of first-class pipetting and imaging technologies, and MACHEREY-NAGEL GmH Co. KG, recognized manufacturer and worldwide supplier of high quality products for the preparation of DNA, RNA and proteins, based on e.g. filter and silica materials, ultra filtration membranes, and magnetic beads, have signed a non-exclusive collaboration for the joint development of applications to automate MACHEREY-NAGEL kits on CyBio liquid handling instruments.

The cooperation focuses on the automation of nucleic acid preparation from various biological sample materials and the purification of PCR products, e.g. for subsequent sequencing and cloning experiments. Due to continuous advancement of the brands NucleoSpin®, NucleoMag und NucleoFast, MACHEREY-NAGEL has gained a worldwide leading position in this field.

For CyBio the cooperation is a further milestone to strategically strengthen the company’s position in genomics. The new CyBi®-GeneRobots product family has been especially designed for genomics applications and offers specific solutions for varying automation levels. CyBi®-GeneRobots incorporate the well-known pipettors CyBi®-DiluSpro, CyBi®-Well vario, CyBi®-Genomics Workstation and CyBi®-RoboSpense. Their robustness, precision, and user-friendliness are a result of CyBio’s long-term experience in the development of high quality pipetting systems for high-throughput screening in drug research.

The cooperation of both partners enables the easy automation of MACHEREY-NAGEL’s innovative DNA/RNA preparation kits with CyBio’s liquid handling instruments, addressing a broad range of customers with diverse demands regarding application, automation, and throughput. Important advantages of MACHEREY-NAGEL kits are the specific product development and the kit modularity to meet the application needs. Robust chemistry can be combined with microplate types of the customer’s choice. Complemented with comprehensive kit accessories, the user can benefit from fast automation implementation and highly reliable results.

The cooperation aims to jointly develop and market a continuously growing series of application notes, which can be accessed via the article webpage.

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Analytik Jena GmbH+Co. KGCompany website

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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CyBio and MACHEREY-NAGEL collaborate to develop applications for automated DNA/RNA preparation