CyBi®-FeliX as a Turnkey Liquid Handling Solution for Cellular and TOX Assays

6 Jan 2014
Kerry Parker
CEO

Product news

Stop by the CyBio booth # 429 to discover the CyBi®-FeliX, a fully automated liquid handling platform, plus the new 1536-channel pipetting head for CyBi®-Well vario.

Join CyBio at SLAS 2014 as we introduce the latest innovations in liquid handling technologies tailored to user's daily challenges.

CyBio tutorial at SLAS
Date: Tuesday, January 21
Time: 2:00 pm – 2:45 pm (45 minutes)
Room: 24C
San Diego Convention Center

REGISTER NOW

The suitability of CyBi®-FeliX as an assay ready, compact liquid handling platform is exemplified in the automation of two popular assays: Cisbio’s HTRF® cellular phospho-assays and CETICS’ TOXXs Analyzer for FADU-genotoxicity. HTRF® cellular kinase phospho-assays provide an ideal phosphodetection readout enabling screening of signaling processes in cells – easily automatable on the CyBi®-FeliX. Furthermore, CyBi®-FeliX was used to automate the FADU-genotoxicity assay. This process improved reproducibility and throughput, simplified handling and enhanced sensitivity and speed.

The CyBi®-FeliX is based on 25 years of liquid handling experience to support your applications like filling of plates and tubes, creating reaction set-ups for PCR and next generation sequencing, ELISA, hit picking or pooling of samples and serial dilutions. The platform can be adjusted to any application requirements through the right combination of pipetting heads and accessories at any time.

Join CyBio at SLAS 2014 and learn more about CyBio’s extraordinary automation solutions at booth #429.

CyBio FeliX

Analytik Jena GmbH+Co. KG

CyBio FeliX – Flexible Benchtop Liquid Handling Flexible pipetting platform for fully automated single to multichannel liquid handling. Discover the new accompanying CyBio FeliX SELECT Head with 8 independent channels and volumes for your hit picking, normalization and pooling applications.

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CyBio Well Vario

Analytik Jena GmbH+Co. KG

The CyBio Well Vario is CyBio´s automated, simultaneous pipetting platform which can be equipped with 11 interchangeable pipetting heads to offer highest pipetting precision and flexibility in a compact design. A large variety of disposable tips, highly precise ceramic tips or glass capillaries allow liquid transfers in a broad volume range of 4 orders of magnitude (25 nl up to 250 µl) on one pipetting system. 14 different capillary magazines are available for CyBio´s Capillary Head, which is especially designed for precise low-volume compound transfers (25—1000 nl). The CyBio Well vario is compatible with many specific accessories and can be adapted to every screening environment to create powerful liquid handling platforms for today and tomorrow. Optional stacker or dispenser integration together with the involvement of versatile peripheral devices can be easily implemented. Challenging liquid handling applications like working in high density microplate formats or in HTS environments can be easily achieved. CyBio´s outstanding customer service and application support is a well appreciated inherent part of every CyBio Well vario system. CyBio Well Vario Features: Extremely flexible through enormous volume spectrum Highest precision in the whole volume range Unique pipetting technology prevents cross contamination Easy application set-up using CyBio Composer software Saves reagent costs with accurate low volume pipetting

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ADME-ToxicologyADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.Robotic WorkstationsRobotic workstations are automated platforms enabling the user to perform high-throughput, multi-application processes, from sample preparation tasks such as PCR set-up, DNA purification and NGS library preparation, to integrated sample prep and analysis workstations. Automation makes processes consistent, fast, precise and fully walk-away. Find the best robotic workstations in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Automated Liquid HandlingAutomated liquid handling equipment is used to mix, dilute and dispense allotted volumes of liquid into microplates and other vessels automatically. The robotic, liquid handling arms can dispense from single channel to 3456 multichannel as well as operate nanoliter dispensing, enabling high throughput of samples. Find the best automated liquid handlers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.SLASThe Society for Laboratory Automation and Screening (SLAS) is an organization focused on laboratory automation, high-throughput screening, and biotechnology innovation. SLAS promotes scientific advancements through conferences, publications, and industry collaborations. Liquid Handling WorkstationLiquid handling workstations automate the process of sample preparation, improving accuracy and efficiency. These systems are essential for high-throughput applications in biological, chemical, and pharmaceutical research, reducing human error and increasing reproducibility. Workstations come equipped with robotic arms, pipetting tools, and other accessories to streamline lab workflows. Explore liquid handling workstations in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.ScreeningUsing robotics, data processing and control software, liquid handling devices and sensitive detectors, screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests.Toxicology Screening